Tumor Hospital of Xinjiang Medical University

Diagnostic value of plasma TFF3‐centered combined biomarker panel in early gastrointestinal cancer

ABSTRACT Gastrointestinal (GI) tumors represent a significant global health burden, necessitating robust strategies for early detection. However, the clinical utility of conventional protein biomarkers such as carcinoembryonic antigen (CEA), carbohydrate antigen 19‐9 (CA19‐9) in...

Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence

The absence of accurate, noninvasive, scalable screening tools keeps early esophageal cancer (EC) detection a global health challenge. Although noncontrast computed tomography (NC CT) is widely accessible, the esophagus is a hollow tubular structure prone to collapse and motion a...

Incidence, Management, and Clinical Outcomes of Cardiovascular Adverse Events in Patients Receiving ALK Inhibitors for Advanced Non-Small Cell Lung Cancer: A Real-World Single-Center Analysis

Cardiovascular adverse event (CVAE) profiles across ALK-TKI generations remain incompletely characterized in real-world practice. A retrospective study of 235 ALK-rearranged NSCLC patients receiving first-, second-, or third-generation ALK-TKIs assessed CVAE incidence, severity,...

Methionine addiction in oral squamous cell carcinoma: a metabolic vulnerability targeted by engineered bacteria

Metabolic reprogramming is a defining hallmark of malignant transformation, and tumor-specific amino acid addiction has emerged as a promising therapeutic axis for precision oncology. Oral squamous cell carcinoma (OSCC) is an aggressive head and neck malignancy marked by limited...