Tongliao Academy of Agricultural Sciences

A case of neonatal gastric perforation misdiagnosed as neonatal necrotizing enterocolitis

Rationale: Neonatal gastric perforation (NGP) is a rare but life-threatening neonatal acute abdominal condition. Its clinical and imaging manifestations may overlap with those of necrotizing enterocolitis (NEC), making accurate preoperative localization of the perforation site ch...

Single-cell landscape reveals PLPP2 upregulation underlying radiotherapy resistance and immune microenvironment remodeling in pancreatic cancer

The main purpose of this study was to investigate the molecular mechanisms underlying radiotherapy resistance in pancreatic cancer by integrating single-cell transcriptomic analysis with multicenter clinical cohorts. Using machine learning algorithms and genomic data, we identifi...

Exploring the association between gastroesophageal reflux disease and hyperlipidemia through bioinformatics and Mendelian randomization

Observational research has found a relationship between gastroesophageal reflux disease (GERD) and hyperlipidemia (HLP). This study explored the relationship between GERD and HLP using bioinformatics and Mendelian randomization (MR) methods. We first conducted bioinformatics anal...

Mechanism of miR-217 in suppressing pancreatic cancer progression by targeting ENO1

Abstract Objective This research was designed to investigate the functional impact of miR-217 in modulating proliferative activity and apoptotic processes in pancreatic carcinoma cells and to investigate its associated molecular mechanisms. Methods Five matched pairs of pancreati...