Tomsk Polytechnic University

Artificial-Lift System Control: A Reduced-Order Transient Model for Real-Time Predictive Control of Electrical Submersible Pump Wells

Unstable well operations, driven by reservoir depletion, high gas–oil ratios, unstable inflow, and surface network interactions, have become a major challenge in modern production — especially in Western Siberian fields — causing flow instabilities and production losses. While nu...

Design, Synthesis,and Evaluation of Alkoxyamine AnticancerProdrugs Bearing Galactoside as an Enzyme-Activated Trigger

Abstract Enzyme-induced cytotoxicity can be considered the main challenge in modern cancer therapy that provides unique opportunities for targeted apoptosis. To address this challenge, we implemented enzyme-triggered activation of alkoxyamine–galactose conjugates with the formati...

Quasi-Experimental Field Assessment of Haul-Road Maintenance Effects on Fuel Consumption, Cycle Time and Mechanical Loading of Open-Pit Dump Trucks

Haul-road condition in open-pit mining affects fuel consumption, transport-cycle throughput and dump-truck mechanical loading. This study conducted a quasi-experimental field assessment of local maintenance effects on severely degraded road segments. The full cycle register conta...