Tokyo Metropolitan Tama Medical Center

Preoperative prognostic stratification of high-risk resectable pancreatic cancer: combined Podxl/itgb1 expression in EUS-FNAB specimens as a prognostic biomarker

Neoadjuvant chemotherapy with gemcitabine and S-1 (NAC-GS) is a conditionally recommended treatment for resectable pancreatic ductal adenocarcinoma (PDAC) in Japan. However, therapeutic efficacy remains limited in a subset of patients who lose surgical opportunities due to tumor...

Perceptions and information needs regarding household exposure to anticancer drugs among family members living with patients receiving outpatient chemotherapy in Japan: A qualitative descriptive study

Introduction As outpatient chemotherapy has become increasingly common, family members may be exposed to anticancer drugs in daily life through contact with patients' body fluids and contaminated environments. However, little is known in Japan about family members' perceptions of...

Aspirin Omission at the Time of Primary Percutaneous Coronary Intervention in STEMI

BackgroundThe safety of omitting up-front treatment with aspirin during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear. MethodsWe conducted a multicenter, open-label, randomized trial in Japan i...

Risk and Impact of Cytomegalovirus Infection in Bullous Pemphigoid Patients Treated With Immunosuppressive Agents

ABSTRACT Severe infection is associated with increased mortality in patients receiving systemic corticosteroid therapy, including those with bullous pemphigoid (BP). Cytomegalovirus (CMV) reactivation represents a highly probable and underrecognized cause of death in immunosuppre...