Tokyo Metropolitan Neurological Hospital

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

WHO CNS5 mandates integrated histo-molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low- and lower-middle-income countries (LICs/LMICs), limiting implementation of molecularly in...

Clinical and molecular characteristics of thalamic gliomas in adults: prognostic impact of TERT promoter mutation

BACKGROUND: Adult thalamic gliomas (ATGs) are rare and biologically heterogeneous tumors. Although the 2021 World Health Organization (WHO) classification designates all diffuse midline gliomas (DMGs), H3-altered, as grade 4, accumulating evidence suggests that adult thalamic DMG...

Nutritional Factors and Weight Loss Predict Tracheostomy‐Free Survival in Multiple System Atrophy

BACKGROUND: Multiple system atrophy (MSA) leads to progressive weight loss and nutritional decline, yet the prognostic significance of specific nutritional factors remains unclear. OBJECTIVES: This study aimed to examine the prognostic value of nutritional parameters, including p...