Tokyo Dental College

Clinical Study of Bullous Pemphigoid With Oral Mucosal Symptoms After Oral Administration of Dipeptidyl Peptidase‐4 Inhibitors

ABSTRACT Dipeptidyl peptidase‐4 (DPP‐4) inhibitors are widely used for diabetes treatment. However, reports of DPP‐4 inhibitor‐associated bullous pemphigoid (BP) have been increasing. This study examined 12 cases of BP with oral mucosal lesions associated with DPP‐4 inhibitor the...

Optimizing post-space drying: insights from an in vitro study using standardized three-dimensional-printed models

Objectives: This study aimed to evaluate the efficiency of four post-space drying methods using standardized three-dimensional (3D)-printed resin tooth specimens, with emphasis on clinical implications for adhesive post retention. Methods: Maxillary central incisor models with po...

Orthodontic and surgical treatment patterns in hemifacial microsomia: a retrospective multi-institutional study in Japan

Hemifacial microsomia is a congenital craniofacial condition characterized by variable facial asymmetry and mandibular hypoplasia. Its management often requires long-term multidisciplinary care, including orthodontic and surgical treatment. However, multi-institutional data on tr...

Survey on Dental Trauma, Head and Neck Injuries, and Mouthguard Use in Wrestlers at the 77th National Sports Festival: First Report

BACKGROUND/AIM: Wrestling is a high-intensity contact sport in which head, neck, and oral injuries occur frequently. However, comprehensive investigations specifically focusing on dental trauma among wrestlers remain limited. The aim of this study was to assess the prevalence of...

Lymph node development in human fetuses with special reference to the initial lymphocyte aggregation and intranodal sinuses

A mouse lymph node develops inside of five lymph sacs in the trunk. However, there are uninvestigated, numerous peripheral nodes. We chose histological sections from 38 human fetuses at approximately 8-31 weeks of gestational age (36 to 260 mm of crown-rump length). Three sites o...

Parathyroid hormone exposure frequency regulates spatiotemporal coupling during bone remodeling in a functional bone model

Abstract Bone homeostasis is maintained by coupling, in which osteoclast-mediated bone resorption is followed by osteoblast-mediated bone formation at the same site. Parathyroid hormone (PTH), including the PTH(1-34) analog, exerts distinct anabolic and catabolic effects on bone...