Toho University

Electrochemical Ammonia Oxidation Catalyzed by Ruthenium Complexes Bearing 4,4’-Substituted Bipyridine Dicarboxylate Ligands

Abstract We have examined electrochemical ammonia oxidation catalyzed by ruthenium complexes bearing 4,4’-substituted 2,2’-bipyridine-6,6’-dicarboxylate (bda) ligands and axial isoquinoline ligands. Bulk electrolysis revealed that a ruthenium complex bearing 4,4’-dimethyl substit...

Complication-attributable admission episodes after shunt surgery for idiopathic normal pressure hydrocephalus in Japan: a scenario-based micro-costing analysis of hospital margins under DPC/PDPS and fee-for-service

Shunt-related complications after surgery for idiopathic normal pressure hydrocephalus (iNPH) generate repeat admissions, procedures, and bed use, but their provider-side financial consequences depend on the reimbursement rule. Evidence on hospital accounting margins under Japan’...

Comparative Short-Term Clinical Events Associated with Molnupiravir and Ensitrelvir for COVID-19: A Retrospective Cohort Study Using Community Pharmacy Records in Japan

Molnupiravir and ensitrelvir are widely used for outpatient coronavirus disease 2019 treatment; however, real-world safety comparisons remain limited. This retrospective cohort study evaluated acute clinical event risks over a 29-day follow-up using community pharmacy records fro...

Genomic Analysis of an IMP-1-Producing Atlantibacter hermannii Bloodstream Isolate Carrying a Transferable blaIMP-1-Harbouring IncHI2/pST1 Plasmid Related to Historical Enterobacterales Plasmids in Japan

Atlantibacter hermannii is an uncommon member of the Enterobacterales rarely associated with human infection, and genomic data on antimicrobial resistance in this species remain limited. Carbapenemase-producing A. hermannii isolates have rarely been described. We characterized an...

Decision-making for emergency craniotomy in traumatic intracranial hemorrhage with severe thrombocytopenia and coagulopathy in a patient with suspected acute leukemia: A case-based review

Background: Emergency craniotomy for traumatic intracranial hemorrhage is time-dependent, yet surgery may be futile when profound thrombocytopenia and coagulopathy prevent hemostasis and severe brain swelling is already present. Case Description: A young adult man with traumatic...

Methenamine, minocycline, metronidazole and pristinamycin (M3P) for multi-drug-resistant Mycoplasma genitalium urethritis: A case series

Objectives Worldwide, Mycoplasma genitalium infections are becoming more resistant to both macrolides and fluoroquinolones - termed multi-drug-resistant (MDR) infections. Combination therapy has shown promise in treating other MDR pathogens. We have previously reported the first...

Mean square estimates for the error terms of sums of the greatest common divisor

Abstract We investigate the mean square behavior of error terms that arise in the summation of gcd ( n 1 , … , n k ) $\gcd (n_1,\ldots ,n_k)$ gcd left parenthesis n 1 comma ellipsis comma n Subscript k Baseline right parenthesis with n 1 … n k ≤ x $n_1\ldots n_k \le x$ n 1 ellips...

False Vacuum in Coupled-Frustrated Multi-Component Superconductors

A local minimum state, energetically inequivalent to the global minimum, can emerge in a coupled-frustrated multi-component superconductor. This local minimum state is metastable when it occupies the entire system. However, when a global-minimum domain appears within the metastab...

Association between central sensitization symptoms and cold hypersensitivity severity in older adults: a cross-sectional analysis from the Otassha Study

Abstract Introduction: Cold hypersensitivity (Hie) is a common complaint among older adults in East Asia and has traditionally been attributed to peripheral circulatory dysfunction. However, emerging evidence suggests that central sensitization (CS) may also contribute. This stud...

Minimally invasive cardiac surgeries in 2023–annual report of the Japanese association for minimally invasive cardiac surgery

Abstract Objective To establish updated nationwide perioperative benchmarks for minimally invasive cardiac surgery (MICS) in Japan by presenting the 2023 annual report and summarizing procedural trends from 2021 to 2023. Methods Data on mitral valve (MV) surgery, aortic valve rep...

Evaluation of the UK Myeloma Research Alliance risk profile in transplant‐ineligible multiple myeloma patients treated with novel agents

Summary The heterogeneity of multiple myeloma (MM) significantly impacts treatment outcomes. Myeloma risk profile (MRP), introduced by the UK Myeloma Research Alliance, is a novel prognostic model for patients with transplant‐ineligible newly diagnosed MM (TIE‐NDMM) utilizing eas...

Ecological momentary assessment of the relation between affect and functional dizziness symptoms: a pilot study

Associations between dizziness symptoms and psychological factors have been reported, but evaluating this through questionnaires alone risks recall bias. In this study we used ecological momentary assessment to clarify the associations between positive affect (PA), negative affec...

Phenotypic screening of hypervirulent Klebsiella pneumoniae using tellurite resistance and carbohydrate fermentation testing

ABSTRACT Phenotypic identification of hypervirulent Klebsiella pneumoniae in routine laboratories remains challenging. We evaluated tellurite resistance and selected carbohydrate fermentation tests as phenotypic tools for screening hypervirulent strains and improving lineage iden...

Reciprocal relationships between stimulus duration, electroencephalography features, and cortical spreading depression during electroconvulsive therapy

Abstract Electroconvulsive therapy (ECT) is effective for treating depression. Recent studies suggest that ECT can induce cortical spreading depression (CSD), which may have clinical benefits. However, the probability of CSD induction and its influence on therapeutically relevant...

Serum anti-POTEE antibodies as a novel serological biomarker for early detection and prognostic stratification in gastrointestinal cancers

Abstract Background Given the highly aggressive nature of gastrointestinal cancers, the identification of novel biomarkers for diagnosis and prognosis is of considerable clinical importance. Methods Candidate cancer-testis (CT) antigens were first screened using RNA-sequencing da...

Minimally invasive deformity correction using microendoscopic extraforaminal lumbar interbody fusion (ME-ELIF) for adult spinal deformity: a case report

Background: Adult spinal deformity (ASD) is associated with progressive sagittal and coronal imbalance, leading to functional decline and decreased quality of life. While minimally invasive approaches, such as lateral lumbar interbody fusion, have gained popularity, they pose ris...

Epidemic Computing: a registration-free best-effort distributed computing model for unmanaged device crowds

Crowds carry a large amount of idle computing capacity, but no entity can enumerate the devices. Managed distributed computing mobilizes only the registered fraction of the crowd, and most capacity remains unused when few register. We propose Epidemic Computing (EC), in which the...

Epidemic Computing: a registration-free best-effort distributed computing model for unmanaged device crowds

Crowds carry a large amount of idle computing capacity, but no entity can enumerate the devices. Managed distributed computing mobilizes only the registered fraction of the crowd, and most capacity remains unused when few register. We propose Epidemic Computing (EC), in which the...

Associations of prior fracture site with physical function and daily living in older adults without certified long-term care needs: insights from a community-based survey

Fractures are a major health concern among older adults and may contribute to declines in physical function and independence. However, their impact may differ by anatomical site. This study examined associations between fracture site and health status, including physical function...