Tobacco Research Institute

Adsorption of the dinotefuran enantiomers by Mg‐modified peanut shell biochar: mechanism, site identification, and density functional theory validation

Abstract BACKGROUND The chiral pesticide dinotefuran, a neonicotinoid insecticide with high water solubility and persistence, poses significant ecological systems risks by interfering with the structure and functions of aquatic ecosystems and accumulating progressively through th...

Mechanistic Decoupling of the cis - and trans -Cleavage Activities of Cas12a via Phosphorothioate-Induced Kinetic Trapping

Abstract CRISPR-Cas12a is widely utilized for genome engineering and nucleic acid diagnostics, being distinguished by its indiscriminate single-stranded DNA (ssDNA) trans-cleavage activity triggered by its specific cis-target recognition. However, the precise kinetic coordination...