Tibet Autonomous Region People's Hospital

Distinct Etiological and Clinical Patterns of Acute Mesenteric Ischemia at High Altitude: A Retrospective Comparative Study

Chen, Chen, Yang, Li, Xu, Fan, Xu, Zhijuan Liu, and Dong Wu. Distinct etiological and clinical patterns of acute mesenteric ischemia at high altitude: a retrospective comparative study. High Alt Med Biol. 00:00–00, 2026. Background: Acute mesenteric ischemia (AMI) is a life-threa...

The impact of sleep quality on cognitive function in residents of high altitude areas: a cross-sectional study

This study aims to explore the current status of cognitive function among community residents in high-altitude areas, and analyze the influence of sleep quality on cognitive function, so as to provide a theoretical basis for developing intervention strategies to improve the cogni...

A dual-functional, responsive nanomodulator alleviates pyroptosis-associated lung injury in ARDS by selectively suppressing the cGAS–STING signaling axis

Injury and inflammation mediated by pulmonary endothelial cell pyroptosis are crucial factors in the progression of acute respiratory distress syndrome (ARDS). Although blocking the cyclic GMP‒AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling pathway is a promi...

PediatricLiver score: a novel risk score for screening elevated liver stiffness in the pediatric population (CHESS2401)

Given the looming crisis of rapid increase in childhood obesity globally, chronic metabolic diseases have consequently emerged but without sufficient awareness among children. Reliable and accessible screening tools thus are required to screen for significant liver fibrosis in th...

Pathogen detection and gut microbiota analysis in subcutaneous abscesses in goats

Subcutaneous abscesses in goats result in carcass condemnation, reduced milk and wool production, growth retardation, and increased mortality, thereby causing substantial economic losses in goat production systems. This study investigated the major pathogens associated with subcu...

Machine learning identifies plasma-derived exosomal miRNAs associated with low muscle mass in Tibetan patients with rheumatoid arthritis

Sarcopenia poses a significant health burden in aging populations, particularly among patients with rheumatoid arthritis (RA), but current diagnostic approaches face limitations in early detection. This study aims to identify plasma-derived exosomal miRNA features associated with...

Diagnosis and Management of Chronic Endometritis: Effects on Postoperative Pregnancy Outcomes in Endometriosis Patients with Proximal Tubal Obstruction Undergoing Hysteroscopic Tubal Catheterization and Laparoscopy

Background: This study aims to investigate the impact of chronic endometritis (CE) diagnosis and treatment on pregnancy outcomes during hysteroscopic fallopian tube catheterization combined with laparoscopy in infertility patients with pelvic endometriosis (EMS) and proximal tuba...

Associations of altitude, physical activity, and body mass index with blood pressure components and grip strength in older adults with elevated blood pressure living at 3100–4500 m in Tibet: a cross-sectional study

High-altitude environments may influence cardiovascular and muscle function in older adults. We examined blood-pressure components and grip strength across three Tibetan altitude sites and their associations with residential altitude, physical activity, and body mass index (BMI)...

The platelet-to-high-density lipoprotein cholesterol ratio as a potential biomarker linking tobacco exposure to accelerated reproductive aging in women

Female reproductive aging, commonly reflected by menopausal age and reproductive lifespan, is influenced by environmental exposures and metabolic health, and tobacco exposure has been associated with earlier menopause and shortened reproductive lifespan. Because this association...

Postoperative pulmonary complications after high-altitude thoracic surgery requiring one-lung ventilation: a single-centre retrospective cohort study

Abstract Background Postoperative pulmonary complications (PPCs) are common adverse outcomes after thoracic surgery and one-lung ventilation (OLV). Their reported incidence varies with endpoint definition and ascertainment. Lower inspired oxygen partial pressure may alter periope...

Genetic diversity, haplotype structure, and population dynamics of Echinococcus granulosus isolates from human cystic echinococcosis in Tibet, China

Cystic echinococcosis (CE) is a globally important zoonotic disease caused by the larval (metacestode) stage of Echinococcus granulosus (sensu lato), a parasite complex characterized by marked genetic heterogeneity across geographical regions. The Tibet Autonomous Region (TAR) of...