Tianjin Third Central Hospital

Recent Advances in Nanotechnology for Targeted Protein Degradation

Mutations or overexpression of proteins contribute to the pathogenesis and progression of numerous diseases, including cancers and neurodegenerative disorders. Traditional small-molecule inhibitors have played a crucial role in treating these diseases; however, they still face se...

White Blood Cell to HDL ‐C Ratio and Sarcopenia: A Dual‐Cohort Analysis Including Exploratory Insights on Hepatitis B History

ABSTRACT Background Sarcopenia, driven by inflammation and lipid dysregulation, lacks inexpensive screening tools. The white blood cell to HDL‐C ratio (WHR) integrates these pathways, but its utility for sarcopenia screening remains unvalidated. Objective This study evaluated the...

Prognostic significance of adropin with Grace and Gensini scores for in-hospital outcomes in ST: elevation myocardial infarction patients

This prospective cohort study investigated the prognostic value of serum Adropin in patients with ST-segment elevation myocardial infarction (STEMI) and its incremental predictive utility beyond traditional GRACE and Gensini scores. A total of 508 participants were enrolled, incl...