Tianjin Stomatological Hospital

Osteoporosis treatment via programmed delivery of IRF5 siRNA to macrophages in bone tissue combined with ROS scavenging

Postmenopausal osteoporosis (PO) is not merely a consequence of increased osteoclast activity. Estrogen deficiency induces oxidative stress and pro-inflammatory M1 macrophage polarization in bone tissue, thereby sustaining osteoclastogenic stimuli and pathological bone resorption...

Why Peri‐Implant Tissues Are Susceptible to Inflammatory Breakdown—Single‐Cell Transcriptomics Reveals Immune Priming in Clinically Healthy Peri‐Implant Mucosa and CXCR2 + Neutrophil Activation in Peri‐Implantitis

ABSTRACT Aim Peri‐implant tissues are more susceptible than gingiva to rapid inflammatory breakdown, but the cellular basis of this vulnerability remains unclear. This study investigated (1) whether clinically healthy peri‐implant mucosa already displays an immune landscape disti...

Incidence and predictors of root resorption after delayed replantation of permanent teeth

Root resorption is a common but unpredictable complication after delayed replantation of avulsed permanent teeth. Evidence from real-world settings regarding its long-term incidence and associated clinical factors remains limited. This study aimed to determine the incidence of ro...

A Mini Review of Functional Hydrogels for the Treatment of Oral Diseases: Opportunities and Future Prospects

Oral health represents a cornerstone of systemic health. Driven by diverse dietary structures and lifestyle habits, nearly everyone is affected by common oral diseases, including oral ulcers, tooth discoloration, and dental caries, etc. However, limited by the inherent properties...

Postoperative pain and 12-month periapical healing after Er: YAG laser–activated versus ultrasonic irrigation: a randomized controlled trial

Abstract Background This randomized controlled clinical trial evaluated contemporary irrigation activation strategies by integrating patient-reported postoperative pain with 12-month radiographic healing outcomes. Er: YAG laser–activated irrigation using photon-induced photoacous...

Sella turcica dimensions in patients with severe skeletal malocclusion using cone-beam computed tomography: a retrospective observational study

Abstract Background As traditional two-dimensional cephalometric analyses of skeletal malocclusions often fail to capture complex craniofacial variations. Recent advances in three-dimensional (3D) imaging have highlighted the correlation between sella turcica morphology and skele...

Comparative efficacy of irrigation activation systems in root canal cleanliness: a region-specific analysis of debris and smear layer removal

This study aimed to compare the efficacy of four irrigation activation systems against conventional needle irrigation (CNI) in removing debris and smear layer from root canal. Forty human single-rooted teeth premolars were instrumented to a consistent size and randomly divided in...

Serum and salivary uric acid levels in oral submucous fibrosis: a systematic review and meta-analysis

This study aimed to evaluate differences in serum uric acid (SeUA) and salivary uric acid (SaUA) levels between patients with oral submucous fibrosis (OSF) and healthy controls. PubMed, Embase, Web of Science, Google Scholar, and the Cochrane Library were searched for studies rep...