The Pirbright Institute

Evaluation of the Safety and Immunogenicity of a Peste Des Petits Ruminants (PPR), Sheep and Goat Pox (SGP) and Contagious Caprine Pleuropneumonia (CCPP) Multivalent Vaccine (JOVAC-Combo®) Under Field Conditions in Somalia

Peste des petits ruminants (PPR), sheep and goat pox (SGP), and contagious caprine pleuropneumonia (CCPP) are diseases of small ruminants and are the major constraints to livestock trading in Africa, the Middle East, and Asia. Vaccination against these diseases individually is ch...

Pericyte dysfunction alone may be insufficient to drive tick-borne orthoflavivirus non-structural protein 1-mediated microvascular permeability

The emerging tick-borne flaviviruses Alkhumra haemorrhagic fever virus (AHFV) and Kyasanur Forest disease virus (KFDV) can cause severe haemorrhagic disease, yet the mechanisms driving this vascular leakage remain unclear. The microvascular capillaries and post-capillary venules...

Impact of a multi-strain probiotic in real-world women with perimenopause symptoms: a single-arm, virtual pilot study

Perimenopause is characterised by fluctuating ovarian hormones and a heterogeneous, multisystem symptom profile that can substantially impair quality of life (QoL). Non-hormonal management options remain limited for those unable/unwilling to use hormone replacement therapy. Emerg...