The London College

A data-driven framework to identify restenosis-prone regions in femoral arteries from geometric and inflow waveform parameters

Haemodynamic indices derived from computational fluid dynamics (CFD), such as time-averaged wall shear stress (TAWSS) and oscillatory shear index (OSI), are closely associated with restenosis risk in peripheral arterial disease (PAD). We present a machine learning-reduced order m...

How effective are interventions at enhancing preschool children's empathy? A meta-analytic review

Empathy, defined as sharing and understanding others’ emotional experiences, is key to the formation of social groups and plays an important role in children’s social development. While enhancing this skill in early education has been a focus in the field, whether trainings emplo...

A new megaraptoran dinosaur from the Lower Cretaceous Wessex Formation, UK, and its implications for theropod evolution and biogeography

Abstract Theropod dinosaur remains from the Barremian (Lower Cretaceous) Wessex Formation of the Isle of Wight, UK, are rare and often fragmentary. Here, we present a previously undescribed braincase from this formation that represents a new coelurosaurian, Invictibellatrix amber...

Frequency of plastic occurrence varies across phylogeny but not ecology in seabirds

Seabirds are especially vulnerable to ingesting plastic pollution. However, we have a limited understanding of which traits might increase their risk of plastic ingestion. Here, we use a dataset of seabird plastic occurrence records (93 281 birds from 240 species) to investigate...

Addition of chemotherapy to radiotherapy promotes progenitor-exhausted CD8⁺ T-cell clonal dominance in head and neck cancer

Abstract Concomitant chemoradiotherapy (CRT) is a standard-of-care treatment for unresectable locally advanced head and neck squamous cell carcinoma (LA-SCCHN), but its immune effects, particularly relative to radiotherapy (RT) alone, remain incompletely understood. Using syngene...

Cranial anatomy of the Middle Eocene Egyptian crocodylian Herugavialis cairensis provides new insights into gavialoid diversity in the Mediterranean region

Abstract Gavialoidea is presently composed of only two extant crocodylian species, the Indian gharial Gavialis gangeticus, and the false gharial Tomistoma schlegelii, both from southeast Asia. However, Gavialoidea displays a rich and near-cosmopolitan diversity in the fossil reco...

Collective Bargaining and Its Implications for Workers and Employers: An Introduction

Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.

Establishing Stakeholder Priorities for Development of a Multi‐Arm Multi‐Stage Platform Trial in Crohn's Disease

ABSTRACT Background and Aims The expanding range of advanced therapies for Crohn's disease (CD) has increased complexity in treatment selection, particularly in refractory disease. Conventional randomised controlled trials are limited in evaluating multiple treatment strategies e...

Preparing the next generation of dental leaders: a scoping review

Aims With ongoing uncertainty about how dental leadership should evolve to meet future real-world challenges, this rapid scoping review evaluated existing literature to identify strategies that most effectively develop leadership skills in dentistry. Methods Multiple sources (Med...

Directed Oxidative Folding of Disulfide-Rich Peptides (DRPs) Using a Pseudoproline Unit: Ion Mobility-Mass Spectrometry (IM-MS) Reveals the Conformational Landscape of the DRP

Abstract Disulfide-rich peptides (DRPs) are attractive drug development scaffolds due to their exceptional stability and specificity. Regioselective disulfide bond formation is often achieved via orthogonal Cys protecting groups or strategic Pro placement. However, Cys protection...

Beyond Ce–U Charge Transfer: Strain and Polarons in Epitaxial Ce1– x U x O2(111)

Abstract The redox chemistry of mixed ceria-based oxides is commonly interpreted in terms of direct charge transfer between neighboring cations. In the Ce1–xUxO2 system, this corresponds to the oxidation of U4+ into U5+ accompanied by the reduction of Ce4+ into Ce3+. In this work...

Mental health link workers in neighbourhood care: a theoretical application of the creative health communication framework

Purpose This article explores the conceptual application of the Creative Health Communication Framework (CHCF) to mental health and wellbeing support within integrated neighbourhood models of care. It proposes the introduction of specialist Mental Health and/or Creative Health Li...

Sex Differences in a Contemporary, Real-World Cohort of Patients with Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis

INTRODUCTION: Tafamidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) versus placebo. ATTR-CM has historically been considered a predominantly male disease, and women are underrepresented in prior studies. Sex-specific data in contemporary pati...

A Modified Delphi Study on the Ethics and Governance of Live Injecting at Aesthetic Conferences. Is There a Better and Safer Alternative?

BACKGROUND: Live clinical demonstrations at aesthetic medicine conferences is common, yet concerns regarding patient safety, commercial influence, and ethical governance. This study established a consensus-based governance framework for live injecting and compared expert and atte...

Does the selective bolding of characters within words improve reading performance in skilled adult readers? Evidence from eye movements

Abstract Reading is core to functioning in our daily lives. Therefore, it is not surprising that numerous tools have been developed to help maximize reading efficiency in both skilled and less skilled readers. In this registered report, we examined the potential of selective bold...

Are Group Interventions Effective at Improving Health Outcomes in Culturally And Linguistically Diverse (CALD) Populations With Chronic Conditions? An Umbrella Review

Abstract Culturally and linguistically diverse (CALD) populations experience disproportionate burdens of chronic disease compared to the general population; previous research demonstrated group-based interventions improve health outcomes across various chronic conditions. This um...

Tunable asymmetric swimming in biflagellate microswimmers

Many biological microswimmers can modulate their swimming gait to achieve directional control of motility, especially when performing steering towards specific directional cues. This can be achieved without the need for obvious morphological or structural asymmetries in the form...

SurgAnt-ViVQA: learning to anticipate surgical events through GRU-driven temporal cross-attention

Abstract Purpose Anticipating forthcoming surgical events is vital for real-time assistance in endonasal transsphenoidal pituitary surgery, where visibility is limited and workflow changes rapidly. Most visual question answering (VQA) systems reason on isolated frames with static...

Parallelised detection of bacteria viability using an electrode array and the Exeter Multiscope

Abstract Antimicrobial resistance remains a global existential threat. Given that antimicrobial therapy commonly starts before pathogen identification, rapid and scalable methods capable of determining effective antimicrobial compounds are needed. In this paper, we demonstrate a...

P1.244. Robotic-Assisted Versus Conventional Minimally Invasive Oesophagectomy for Oesophageal Cancer: A Comparative Meta-Analysis of Perioperative and Oncological Outcomes

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – technique Background Robotic-assisted minimally invasive oesophagectomy (RAMIE) is increasingly adopted to improve surgical precision, mediastinal dissection, and surgeon ergonomics. However, its clinical...