The First People's Hospital of Guiyang

Effectiveness and Safety of Fixed‐Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real‐World Study From China

BACKGROUND: This study assessed the real-world effectiveness and safety of a fixed-dose combination (FDC) of metformin and empagliflozin in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This prospective, multicenter, real-world study enrolled consecutive patient...

Collagen-targeted extracellular vesicles from exercised progenitors restore cardiac microcirculation via endothelial AMPK-eNOS-NO axis reactivation

Endothelial dysfunction, driven by impairment of the AMPK-eNOS-NO signaling axis, is a primary defect in diabetic cardiomyopathy (DCM). Extracellular vesicles (EVs) are key mediators of intercellular communication. EVs from exercised conditions possess enhanced bioactivity, but t...

Bedside rapid lactate-creatinine-to-platelet ratio score and short-term mortality prognosis in patients with aspiration pneumonia complicated by sepsis: a multicenter cohort study

This study aimed to investigate the association between the rapid bedside Lactate-Creatinine-to-Platelet Ratio (LCPR) and short- to medium-term mortality prognosis in patients with aspiration pneumonia complicated by sepsis. This retrospective database-based observational study i...

Comparing the efficacy of bronchial artery chemoembolization combined with anlotinib versus anlotinib alone in the treatment of advanced non-small cell lung cancer

To compare the clinical effectiveness and safety of addition of anlotinib to bronchial artery chemoembolization (BACE) compared to anlotinib alone in the treatment of stage IIIA-IIIB non-small cell lung cancer (NSCLC) with no mutated driver genes. The clinical data of patients wi...