The First Hospital of Kunming

Esophageal cancer burden across 48 Asian locations, 2009–2023: demographic decomposition and exploratory projections

Asia carries most of the global esophageal cancer burden, but trends in rates may differ from changes in service demand. We assessed burden across 48 Asian locations during 2009–2023. We analyzed Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 estimates of...

ANGPTL4 is a hypoxia associated candidate linked to immune and vascular phenotypes in ccRCC

Clear cell renal cell carcinoma (ccRCC) is characterized by prominent vascularization and cellular heterogeneity, but reliable biomarkers for angiogenesis and response to targeted therapy remain limited. In this study, transcriptomic data from GEO cohorts (GSE53757, GSE66271, GSE...

Stroke survivors’ health priorities and targeted interventions in home-based post-discharge rehabilitation

<title>Abstract</title> Background This study aimed to describe health problems of the stroke survivors and the corresponding nursing interventions implemented during 12-week home-based post-discharge rehabilitation. Methods This was a descriptive secondary analysis within the co...

Escitalopram for psychological symptoms and cardiovascular outcomes in patients with coronary heart disease: a systematic review and meta-analysis of randomized controlled trials

Patients with coronary heart disease (CHD) often have comorbid depression and anxiety, which worsen prognosis. Escitalopram, a selective serotonin reuptake inhibitor, is used for these symptoms, but evidence on its psychological and cardiovascular effects in CHD is limited. This...