Institution
The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
Recent research
- Health & MedicineOpen access
CAR-based therapies in systemic autoimmunity: from deep immune depletion toward durable immune reset
Systemic autoimmune diseases are sustained by self-renewing networks of autoreactive B cells, antibody-secreting cells, pathogenic T-cell programs and tissue-resident inflammatory niches. Conventional immunosuppression and biologic therapy can reduce disease activity, but often f...
- BiologyOpen access
Vesicular trafficking is a fundamental mechanism that maintains cellular homeostasis, enables precise material transport, and regulates signal transduction in eukaryotic cells. In immune cells, vesicular trafficking supports dynamic membrane remodeling and activation-dependent ve...
- Health & MedicineOpen access
Among the subtypes of endometriosis (EMs), ovarian endometrioma (OE) causes the most direct and progressive damage to ovarian reserve function. This study aimed to identify independent risk factors for OE in patients with EMs, and to develop and validate a clinical classification...
- Health & Medicine
Abstract Piericidins are α-pyridone agricultural antibiotics produced by actinomycetes. To improve their yield and structural diversity from marine-derived Streptomyces psammoticus SCSIO NS126, this study employed homologous recombination to achieve large-fragment knockout of mod...