Texas Medical Center

Clinical Outcomes of Systemic Steroid Use in Children Under 2 with Bronchiolitis and BPD

OBJECTIVES: No guidelines exist for managing children with bronchopulmonary dysplasia (BPD) hospitalized with acute bronchiolitis. This study evaluated clinical practice and outcomes associated with systemic steroid use in children with BPD and acute bronchiolitis. We hypothesize...

Comparative adjuvant therapy to reduce vancomycin-associated nephrotoxicity in an animal model

Vancomycin is a mainstay antibiotic for serious gram-positive infections, but nephrotoxicity remains a major barrier to its optimal use. In this study, we compared the effectiveness of montelukast and zileuton as adjuvant strategies to reduce vancomycin-associated nephrotoxicity....

Non‐contrast CT Markers of Hematoma Expansion and Andexanet Response in Factor Xa Inhibitor‐Associated Intracerebral Hemorrhage: An Analysis from ANNEXa ‐I Trial

In this post hoc analysis of the ANNEXa-I trial (n = 434), we evaluated non-contrast computed tomography (NCCT) markers of hematoma expansion (HE) in factor Xa inhibitor (FXai) -associated intracerebral hemorrhage (ICH). At least one NCCT marker was present in 72.1%, and HE (≥12....