Institution
Texas Medical Center
Recent research
- Health & MedicineOpen access
Importance Skin toxic effects are a common early adverse event of enfortumab vedotin plus pembrolizumab (EVP) therapy, but its association with clinical outcomes in patients receiving first-line therapy remains uncertain. Objective To evaluate the association between treatment-em...
- Health & Medicine
Clinical Outcomes of Systemic Steroid Use in Children Under 2 with Bronchiolitis and BPD
OBJECTIVES: No guidelines exist for managing children with bronchopulmonary dysplasia (BPD) hospitalized with acute bronchiolitis. This study evaluated clinical practice and outcomes associated with systemic steroid use in children with BPD and acute bronchiolitis. We hypothesize...
- Health & MedicineOpen access
Comparative adjuvant therapy to reduce vancomycin-associated nephrotoxicity in an animal model
Vancomycin is a mainstay antibiotic for serious gram-positive infections, but nephrotoxicity remains a major barrier to its optimal use. In this study, we compared the effectiveness of montelukast and zileuton as adjuvant strategies to reduce vancomycin-associated nephrotoxicity....
- Health & MedicineOpen access
In this post hoc analysis of the ANNEXa-I trial (n = 434), we evaluated non-contrast computed tomography (NCCT) markers of hematoma expansion (HE) in factor Xa inhibitor (FXai) -associated intracerebral hemorrhage (ICH). At least one NCCT marker was present in 72.1%, and HE (≥12....