Telethon Institute Of Genetics And Medicine

Addressing the Limits of Emx2 Therapy of Glioblastoma Multiforme by Transgene Insulation and Epigenetic Pharmacological Intervention

Introduction/Objectives: Implicated in the regionalization of the anterior central nervous system (CNS) and the progression of pallial astrogliogenesis, the transcription factor gene EMX2 has been reported to be specifically silenced in several tumors, both non-neural and neural....

Dengue virus serotype classification from complete genomes using a Transformer with chunk-based sequence modeling and explainability analysis

Artificial intelligence is increasingly used for genomic surveillance of infectious diseases, but predictive models must be evaluated under realistic generalization settings and interpreted cautiously. We present XAI-DENFormer, an explainability-oriented framework for dengue viru...