Tecnológico Nacional de México

Exploratory In Silico Evaluation of Microencapsulation Matrices for Indomethacin

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as indomethacin (ID), may produce gastrointestinal adverse effects associated with cyclooxygenase-1 (COX-1) inhibition, motivating the investigation of microencapsulation strategies for modulating drug release. However, protein-...

Elevated puborectalis stiffness measured by endovaginal shear wave elastography is associated with obstructed defecation syndrome

Abstract Obstructed defecation syndrome (ODS) is a common functional disorder in which conventional B-mode ultrasound demonstrates abnormal puborectalis muscle (PRM) behaviour but cannot quantify intrinsic tissue mechanical properties. Shear wave elastography (SWE) provides a qua...

Stereolithography-fabricated polymer composites reinforced with Agave angustifolia Haw bagasse fibers and MWCNTs for PEMFC bipolar plates

The present work investigates novel composites fabricated via stereolithography (SLA) additive manufacturing, consisting of an acrylonitrile butadiene styrene (ABS)-like photopolymer matrix reinforced with Agave angustifolia Haw bagasse fibers (AFs) and multi-walled carbon nanotu...

Multi-criteria kinetic modeling of kerogen hydrothermal conversion: assessing network complexity and model selection

The kerogen-rich oil shale deposits constitute a strategically vital unconventional resource base. However, suitable kinetic studies that represent the reactions for developing appropriate technologies are scarce. This study systematically evaluates the predictive accuracy of kin...

Online algebraic identification–based trial-weight-free modal balancing of asymmetric rotor–bearing systems

Asymmetric rotor–bearing systems exhibit parametric excitation and complex vibration behavior due to unequal stiffness along their principal axes, which significantly complicates conventional balancing procedures. Most existing methodologies require trial weights and multiple rot...

ZnO/p-Si heterostructure for UV sensing and long-range IoT environmental monitoring

The development of low-cost photoconductive ultraviolet sensors with long-range wireless communication remains an attractive approach for environmental monitoring applications. In this work, a ZnO/p-Si photoconductive heterostructure was fabricated by spray pyrolysis and experime...

Anatomical Asymmetry in Adipose Tissue Thickness Alters Heat Transfer During Superficial Thermotherapy: A Computational and Experimental Study

Computer models and protocols commonly used for superficial thermotherapy assume anatomically symmetric tissue geometries. However, anatomical variability, particularly the variability of the adipose tissue thickness, may have a significant impact on heat transfer and cause non-u...

Anthracnose control in avocado using Yamadazyma mexicana encapsulated with whey protein isolate and arabic gum by solution blow spraying

Microencapsulation using solution blow spraying represents an innovative strategy for preserving the viability of biocontrol agents in agricultural bioformulations. This study developed a formulation of Yamadazyma mexicana encapsulated with whey protein isolate and arabic gum, us...

Design, synthesis, drug-likeness, and molecular dynamics evaluations of monobrominated amathamide G analogs as potential ligands for D2-like dopamine receptors

Abstract Dopamine receptors (DRs) are key modulators of physiological and behavioral responses in the central nervous system (CNS), playing a major role in psychotic disorders. Among these, the D2-like members D2R, D3R and D4R are particularly attractive therapeutic targets for t...

Leeuwenhoek in Mexico: new paths in the global circulation of scientific knowledge

Abstract Anthony van Leeuwenhoek (1632–1723) was the first to observe single-celled organisms. Between 1673 and 1723 he sent 189 letters containing scientific observations to the Royal Society, 114 of which were edited into 117 published articles in the Philosophical Transactions...

Non-Destructive Classification of Ataulfo Mango Ripeness Using Color Images and Machine Learning

Automatic classification of Ataulfo mango (Mangifera indica L.) ripeness is essential to ensure consistent quality, standardize post-harvest processes, and reduce the subjectivity of traditional visual inspection, which is unreliable and error-prone. This paper aims to develop a...

Pinoresinol as a Potential c-Myc Complex Modulator: An In Silico Study

The c-Myc oncoprotein is a central regulator of oncogenic transcriptional programs that remains challenging to inhibit directly, necessitating strategies that target c-Myc–associated protein complexes rather than the protein alone. This study conducted an in silico evaluation of...

Ultrasound-Assisted Enzymatic Processing of Grasshopper (Sphenarium purpurascens): Comparative Assessment and Characterization of Protein Hydrolysates

The increasing demand for sustainable protein sources has stimulated interest in edible insects such as the Mexican grasshopper (Sphenarium purpurascens). This study evaluated grasshopper flour as a substrate for producing protein hydrolysates by ultrasound-assisted enzymatic hyd...

Relative gain array–based interaction modification via compensator design: experimental validation on a 2-DOF helicopter

This paper proposes a compensator design methodology based on the Relative Gain Array (RGA) for systematically modifying the steady-state interaction structure of linear multivariable systems. Unlike the conventional use of the RGA as an analysis tool for input–output pairing sel...

‘Like a Fish in the Water’: Subjective Well‐Being and the Alignment of Perceptions of Democracy With Political Structures

ABSTRACT Happiness research has long highlighted the role of national culture, yet few studies distinguish between objective conditions and collective cultural environments in which citizens form political perceptions. Focusing on perceptions of democracy, this study examines how...

Genomic Potential and Climate Resilience of Agave angustifolia Haworth in Raicilla Production

Agave angustifolia Haw. is one of the primary sources for the production of mezcals such as raicilla and tuxca, in western Mexico. In Jalisco, Agave angustifolia evolved from being a pre-Hispanic ritual and food resource (200–1500 CE) to becoming the primary basis for 16th-centur...