Tbilisi State Medical University

Stage-driven mortality and clinical risk stratification among lung cancer patients in Dhaka, Bangladesh: A multi-hospital secondary analysis

Introduction Lung cancer is a major cause of cancer mortality, and patient-level outcome data from Bangladesh remain limited. Locally relevant, interpretable risk-stratification models may help identify patients with higher recorded mortality risk using routinely available clinic...

Open-Loop Deep Brain Stimulation Versus Closed-Loop Responsive Neurostimulation in Drug-Resistant Bitemporal Epilepsy: A Narrative Review

Abstract Drug-resistant bitemporal epilepsy presents a therapeutic challenge when resective surgery is not feasible due to bilateral seizure onset or eloquent cortex involvement. Neuromodulation has emerged as an alternative, with open-loop deep brain stimulation (DBS) and closed...

Delivery of cardiac rehabilitation through hybrid models and alternative settings by country income classification and decade: Comparisons from the International Council of Cardiovascular Prevention and Rehabilitation’s 2025 Global Audit Update

Objective Cardiac rehabilitation (CR) is an outpatient model of secondary prevention that improves patient outcomes, yet use remains limited. Hybrid/alternative CR addresses these challenges, but global availability, structure, and volumes have not been characterized since the pa...

The robotic PIANO: a critical narrative review of surgeon-controlled operative polyphony, human factors, and robotic training

Abstract Robotic surgery can concentrate control of several technical functions at the console, but such concentration does not itself confer clinical independence, reduce dependence on the perioperative team, or improve patient outcomes. We define surgeon-controlled operative po...

From symbolic inclusion to substantive integration: state internship programme in Post-Soviet Georgia

Purpose To evaluate the effectiveness of Georgia's State Internship Programme for graduates from non-Georgian language schools enrolled in the “1 + 4 Programme,” by examining how it supports their professional integration, analysed through the lenses of representative bureaucracy...

Local field potential biomarkers for adaptive deep brain stimulation in Parkinson’s disease: A scoping review

Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the elderly. Conventionally, to combat the symptoms, drugs such as Levodopa and conventional deep brain stimulation (DBS) are routinely used. However, with time, the efficiency of both tr...

Preoperative SGLT2 Inhibitor Use and Outcomes After Major Cardiac Procedures: A Propensity Score-Matched Analysis of the TriNetX Network

Background/Objectives: Sodium–glucose cotransporter-2 (SGLT2) inhibitors improve cardiorenal outcomes in patients with diabetes, heart failure, and chronic kidney disease. Their association with perioperative outcomes after major cardiac procedures remains uncertain. Methods: In...

Effect of probiotic, prebiotic, and synbiotic supplementation on anemia in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials

Anemia is common in hemodialysis patients and reduces quality of life. Gut dysbiosis may contribute. Biotic supplements (probiotics, prebiotics, synbiotics) could help, but evidence is uncertain. This review evaluated their effects on hemoglobin, hematocrit, ferritin, and TIBC. W...

Impact of systemic hormonal imbalances on sebaceous gland disorders: An in-depth review integrating clinical, endocrine, and therapeutic insights

Sebaceous gland disorders (SGDs), including acne vulgaris, seborrheic dermatitis, sebaceous hyperplasia, and hidradenitis suppurativa, are strongly influenced by systemic hormonal regulation. Androgens, insulin, insulin-like growth factor-1 (IGF-1), estrogens, and progesterone mo...