Tang Hospital

Chimeric antigen receptor (CAR)-T cell therapy for solid tumors in pediatric patients: current breakthroughs, dilemmas, and strategies

Chimeric antigen receptor (CAR)-T cell therapy has demonstrated substantial clinical efficacy in pediatric hematologic malignancies; however, its application in pediatric solid tumors remains investigational and is constrained by substantial biological and clinical challenges. Ke...

Serum S100A6, ICAM-1, and S100B and neurocognitive outcomes after pediatric tonsillectomy and adenoidectomy

To investigate the relationship between serum levels of S100 calcium-binding protein A6 (S100A6), intercellular adhesion molecule-1 (ICAM-1), and S100 calcium-binding protein B (S100B) and the development of postoperative delirium (POD) and postoperative cognitive dysfunction (PO...

Severe skeletal and renal complications in SLC4A1-related distal renal tubular acidosis following prolonged treatment interruption: a case report highlighting transition-related vulnerability

Abstract Background SLC4A1-related distal renal tubular acidosis (dRTA), caused by dysfunction of the anion exchanger 1 (AE1), is typically associated with a relatively mild and late-onset phenotype. However, outcomes may vary substantially, particularly in the setting of delayed...