Tan Tock Seng Hospital

IgG4 ‐Related Disease Presenting as Inflammatory Midline Pseudotumor of the Face and Neck

A 78-year-old Chinese woman presented with a one-year history of a progressively enlarging purpuric rash over the central face and nasal dorsum, with subsequent development of a firm midline neck mass. Histopathology revealed dense lymphoplasmacytic infiltrate with fibrosis and o...

Impact of Optical Coherence Tomography Angiography Scan Protocols on Quantitative Microvascular Biomarkers in Diabetic Retinopathy

Purpose: The purpose of this study was to evaluate the influence of optical coherence tomography angiography (OCTA) scan protocols on quantitative measurements of diabetic retinopathy (DR) biomarkers and their diagnostic performance for DR staging. Methods: In this cross-sectiona...

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Abstract Purpose Postsurgical CME is a common cause of suboptimal vision following both unremarkable cataract and vitreoretinal surgery. While there is no widely accepted treatment algorithm, therapeutic options include topical nonsteroidal anti-inflammatory drugs (NSAIDs), corti...

Feasibility, safety, and acceptability of robotic-assisted rehabilitation for patients with knee osteoarthritis

Abstract Total knee replacement (TKR) is an effective treatment for end-stage knee osteoarthritis (KOA), yet optimal preoperative rehabilitation strategies remain undefined. Robot-assisted rehabilitation offers potential advantages in delivering controlled, intensive, and reprodu...

Surgical outcomes of trabecular micro-bypass minimally invasive glaucoma surgery devices in eyes with high myopia: a 24-month retrospective multicenter cohort study

BACKGROUND: To describe outcomes of two trabecular bypass minimally invasive glaucoma surgery (MIGS) devices in highly myopic (HM) eyes with glaucoma up to 24 months postoperatively. METHODS: A retrospective, observational multicenter study of HM eyes (phakic refractive spherical...

P1.156. Outcomes of Curative Esophagectomy in Octogenarians vs Non-Octogenarians With Esophageal Cancer: A Systematic Review and Meta-Analysis

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Esophageal cancer (EC) poses a growing global challenge in the context of an aging population. Evidence on the role of curative esophagectomy in octogenarians is limited. This study aims to compa...

Characterisation of liver disease using quantitative MRI: report of the imaging arm of the ELEGANCE study

Evolving disease aetiology and rising prevalence of chronic liver disease are driving an increase in hepatocellular carcinoma (HCC). Non-contrast quantitative MRI (qMRI) has shown promising capability for characterising liver health and risk of liver related outcomes, but has not...

Risk of new‐incident mental health diagnoses following SARS ‐ CoV ‐2 infection amongst children and young adults in Singapore: a retrospective cohort study

Background Mental‐health‐disorders in children/young adults increased post‐pandemic; however, the absence of linkage to COVID‐19 registries made direct attribution of psychological sequelae to acute infection challenging. Methods Healthcare‐claims databases in Singapore were util...