Tampere University

Assessing Behavioral and Environmental Facets of Obesity Unobtrusively Utilizing Digital Tools: Introducing the BETTER4U Indicators

ABSTRACT Understanding obesity involves evaluating numerous contributing factors. Collecting the necessary data for this can impose a significant burden on both research participants during clinical studies and real‐life deployments of digital tools aiding obesity management. The...

The PISA high performing systems for tomorrow framework: a decolonial reading of the OECD's future-oriented education for human flourishing

Purpose This article critically examines the OECD's High Performing Systems for Tomorrow (HPST) initiative, focusing on how non-Western intellectual traditions – Ubuntu, Confucianism and Buddhism – are referenced in its conceptualisation of education for human flourishing. It inv...

Predicting participation and expenditure on distinct gambling-like mechanics: financial engagement, selective problem gambling effects and a gaming disorder null

Purpose Quantitative work on gambling-like mechanics (GLMs) in video games has largely treated them as a uniform category, overlooking differences in reward structure and similarity to traditional gambling. This study examines predictors of expenditure across three disaggregated...

Child acquisition of complex consonants: The role of oral motor control in developing acoustic targets

Our study examines the role of oral motor control in the acquisition of acoustic targets for lingually complex consonants in Estonian by speakers from four age groups. We focus on children's production of secondarily palatalised and non-palatalised consonants where anatomical dev...

Automating clinical information retrieval from Finnish electronic health records using large language models

Abstract Clinicians often need to search for patient-specific information within electronic health records (EHRs) containing years of heterogeneous longitudinal documentation, a task that can be time-consuming, cognitively demanding, and prone to oversight. We evaluated 14 locall...

The clinical benefit of routine PET/CT imaging in asymptomatic head and neck squamous cell cancer patients one year post-treatment

BACKGROUND: The incidence of head and neck cancer is increasing, creating a growing need for follow-up strategies. The benefit of routine PET imaging beyond six months after treatment in asymptomatic patients remains unclear. OBJECTIVE: To assess whether routine PET/CT or PET/MRI...

Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis

Abstract Introduction The benefits of neoadjuvant therapy (NAT) for pancreatic cancer (PC) with portal venous involvement remain debated. This study aimed to compare the short- and long-term outcomes of surgery with or without NAT in patients with PC with suspected venous involve...

Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk

Prospective evidence linking early-life microbiome development and host genetics with type 1 diabetes (T1D) risk is limited. Here, we describe how gut microbiome maturation and host genetics influence T1D risk in the TEDDY study. We analysed 12,151 longitudinal metagenomes and ho...

JuRa: The Juventas Radar on Hera Mission to Probe Internal Structure of Didymos and Dimorphos Asteroids

Abstract JuRa, the Juventas Radar, is the sounding radar of the Hera/ESA mission on cruise to the asteroid Didymos and its moon, Dimorphos. In 2027, it will, for the first time, do direct observation of the internal structure of an asteroid for the benefit of both science and pla...

Neuropathology of a patient with Parkinson's disease and biallelic expansion in RFC1

This is the first report of neuropathology in biallelic RFC1 expansion-associated Parkinson's disease (PD). It shows a synucleinopathy of intraneuronal Lewy bodies consistent with the clinical PD diagnosis while neuropathological CANVAS (Cerebellar Ataxia with Neuropathy and bila...

Microbial differences and continuity across rectal, vaginal and endometrial sites in obese and normal-weight infertile women

Abstract Background This study characterizes microbial relationships and bacterial transfer across the rectal, vaginal and endometrial microbiomes upon embryo transfer, and evaluates the influence of obesity on site-specific profiles. The Tampere Infertility Microbiome Project (T...

Students’ online credibility evaluation skills across four grades representing three educational levels: factorial invariance and cross-sectional comparisons

Abstract We sought to validate a web-based online credibility evaluation task across four grade levels to provide a robust tool for assessing students’ online credibility evaluation skills and grade-level differences in skills while controlling for text reading order, prior topic...

Practical flow state detection: Entropy-based EEG classification from portable EEG headbands

Flow state, characterized by deep engagement and immersion during challenging activities, represents a valuable mental state with significant implications for learning, performance, and rehabilitation outcomes. While flow has been extensively studied behaviorally, objective neuro...

Emotions in flipped and lecture-based math courses

Background Emotions play an important role in learning. Activating teaching methods, such as flipped learning, can provide positive learning experiences but also pose emotional challenges to students. Aims This intensive longitudinal study investigated 1) how students’ emotional...

Toward Optimized Proteomics Analysis to Detect Bacterial and Host Proteins in Calcified Coronary Artery Plaques

Abstract Coronary calcification is the final stage in coronary heart disease, associated with significantly increased morbidity and mortality. The molecular pathology of calcification and especially events triggering calcification are poorly understood. Metagenomic and molecular...

Basic Psychological Needs and Motivational Constructs Behind Behavioral Intention Toward Hypothetical Technology-Based Solutions for Loneliness

Abstract Today, loneliness is a widely recognized health concern. Technology offers growing opportunities to develop solutions for mental health challenges. To design effective solutions, this study aims to understand the psychological and motivational factors that influence pote...

Connecting Skin and Gut in Dermatitis Herpetiformis: Insights from Gluten Challenge Transcriptomics

Dermatitis herpetiformis (DH) is a dietary gluten -induced autoimmune blistering skin disease. It is hypothesized to be initiated by a small intestinal mucosal immune response. Gluten-free diet (GFD) is the primary treatment for DHdermatitis herpetiformis and effectively resolves...

Concurrent emergency head and cervical spine CT utilization: temporal trends, diagnostic yield, and clinical implications

PURPOSE: To evaluate the diagnostic yield, temporal trends, and clinical implications of concurrent non-contrast head and cervical spine computed tomography (CT) in emergency department trauma patients over a 10-year period. METHODS: This single-center retrospective cohort study...

Process evaluation of a school-based sexual health intervention targeting 13–14-year-olds in Finland

Purpose A systematic approach to conducting process evaluations is essential for understanding the implementation of health interventions and their mechanisms of impact. This study aims to describe the process evaluation of a school-based, social-marketing-principles-utilising se...

Cerebral glucose utilisation during musical emotions: A multimodal functional PET/MRI study:A multimodal functional PET/MRI study

Functional magnetic resonance imaging (fMRI) studies have demonstrated music-induced activation of the blood-oxygen-level-dependent (BOLD) signal across brain networks associated with auditory perception, motor control, and emotion. However, BOLD-fMRI reflects vascular responses...