Taipei Hospital

LDLR variants and higher LDL-C levels are associated with premature coronary disease requiring revascularization in patients with familial hypercholesterolemia-a TCVGH-TPMI cohort analysis

The specific impacts of LDLR and APOB variants on premature coronary artery disease (CAD) that requires revascularization are less explored in Han Chinese with familial hypercholesterolemia (FH). We investigated these genetic drivers within the Taichung Veterans General Hospital-...

Adipose Tissue Browning in MASLD and Its Molecular Mechanisms and Metabolic Crosstalk

PURPOSE OF REVIEW: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly prevalent complication of obesity and metabolic dysregulation, with limited therapies targeting upstream drivers of disease. Adipose tissue has emerged as a central regulator of...