Taihe Hospital

Vaginal microbiome and metabolome profiling identifies candidate signatures associated with persistent high-risk HPV infection

Abstract The role of vaginal microbiota dysbiosis in the progression of human papillomavirus (HPV) infection is increasingly recognized. Yet, the factors determining why only a minority of infections persist and evolve into clinically significant disease remain poorly defined. Fr...

Longitudinal Study on Post‐Traumatic Stress Disorder, Anxiety, and Depression Among Medical Staff in China

ABSTRACT Background Evidence of the longitudinal relationship between anxiety, depression, and post‐traumatic stress disorder (PTSD) is not uniform. This study aimed to explore the dynamic changes, independent factors, and bidirectional predictive relationships of anxiety, depres...

Heart failure may promote breast cancer progression through a Col10a1-associated Tgf-β/Smad-EMT pathway

Heart failure (HF) is clinically associated with aggravated breast cancer (BC) progression; however, the integrative genomic mechanisms underlying this cardio-oncological crosstalk remain poorly understood. We conducted integrative bioinformatics analyses combining weighted gene...

HBV re-activation is associated with increased mortality and dysregulation of oxidative and polyamine metabolism in pre-acute-on-chronic liver failure

Abstract Background/Aims Acute-on-chronic liver failure (ACLF) is one of the deadliest complications of chronic liver disease yet treatment options are sparse. In Asia, HBV-reactivation (HBVr) is one of the most common triggers. Recently, HBV-associated ACLF was associated with d...

Associations and potential utility of composite obesity and metabolic indices for osteoporosis risk assessment in Chinese adult men: a cross-sectional study

Osteoporosis in men is associated with substantial morbidity and mortality, yet simple tools for preliminary risk assessment remain limited. The aim of this study is to examine the associations and potential utility of composite obesity- and metabolism-related indices for osteopo...

Elevated thyroglobulin due to a back musculature schwannoma in differentiated thyroid cancer: a case report

Case presentationOn 29 June 2021, a 36-year-old man with stage T4N1M0 differentiated thyroid cancer presented to the First Affiliated Hospital of Anhui Medical University for radioiodine therapy aimed at eliminating metastases.The patient had previously undergone bilateral radica...

An ioversol-enhanced micro-CT workflow for hematoma visualization and preoperative localization in a murine autologous blood model of intracerebral hemorrhage

Abstract Autologous blood injection produces a discrete striatal clot in mice, but the hematoma is usually confirmed only after brain removal and sectioning, making craniotomy planning difficult for evacuation studies. To address this limitation, we mixed freshly collected autolo...

The effect of cochlear implantation in older adults: an umbrella review of systematic reviews and meta-analyses

INTRODUCTION: Age-related hearing loss is increasingly prevalent and impacts psychosocial wellbeing, cognitive health, and quality of life in older adults. While cochlear implants (CIs) are effective for severe-to-profound loss, their use in the elderly was historically cautious....

Development of a treatment classification system and treatment strategy for ligamentous ossification disease-traditional and innovative surgical strategies

Ligamentous ossification diseases like OPLL and OLF can cause severe neurological compromise. While whole-spine CT identifies ossified segments and MRI reveals cord compression/signal changes, treatment guidelines—especially for multi-level involvement—remain undefined, particula...