Taif University

Multistep synthesis of novel indole–benzimidazole hydrazone hybrids as xanthine oxidase inhibitors: In-Vitro evaluation, molecular docking, MD simulations and DFT studies

This work reports the synthesis of a focused library of indole-benzimidazole hydrazone hybrids ( 17 - 35 ) via a multistep procedure involving thiolation, hydrazination, and Schiff base condensation. The final structures were confirmed using 1 H-NMR, 13 C-NMR, and FT-IR spectrosc...

Thermal-economic performance assessment of heat recovery-oriented design of integrated CCHP-H₂ system; multi-objective optimization with LCA and AdaBoost decision-making

Combined cooling, heating, power systems integrated with hydrogen production (CCHP–H₂) can simultaneously supply useful outputs while improving the utilization of fuel and recoverable thermal energy. The present project proposes a methane-fueled CCHP–H₂ configuration integrating...

Neonatal and Maternal Sepsis in Gulf Cooperation Council Countries, 1990–2023: A Global Burden of Disease Analysis and Forecast to 2050

Introduction: Sepsis remains an important cause of preventable morbidity and mortality, but long-term trends in neonatal and maternal sepsis across the Gulf Cooperation Council (GCC) have not been well characterized. Methods: We analysed Global Burden of Disease (GBD) 2023 estima...

Interfacial synergy in NiO-MnO2-g-C3N4 ternary heterostructure nanostructure for enhanced electrocatalytic water splitting

Developing affordable, highly stable, and efficient bifunctional electrocatalysts for overall water splitting and hydrogen production is essential for advancing clean and sustainable energy technologies. In this study, a ternary heterostructure nanocomposite consisting of NiO, Mn...

Application of soliton theory to plasma confinement and fluid transport: analytical and numerical results for the Akbota equation

Abstract In this paper, an analytical and numerical analysis of the integrable Akbota equation, which is a nonlinear wave equation applicable in the areas of plasma physics and fluid dynamics, is performed. With the help of traveling wave transformation, the governing set of equa...

Reinforcement learning–coupled neural ode modelling reveals ferroptotic resolution failure as a shared dynamical axis linking periodontitis and coronary atherogenesis

The molecular axis underlying the epidemiologically established association between periodontitis and coronary heart disease (CHD) remains undefined at mechanistic, systems-level resolution. Classical comparative transcriptomics captures correlational gene lists but cannot recons...

High-Isolation Super-Wideband MIMO Antenna Based on Elliptical-Ring Geometry for Next-Generation Wireless Applications

In this work, a compact elliptical-shaped multiple-input multiple-output (MIMO) super-wideband antenna with port isolation greater than 17 dB is suggested for use in future wireless communication systems. The simulated outputs indicate a super-wide band from 2 to 30 GHz, with a p...

Medical radiation at the crossroads of complexity and opportunity: New staff perceptions

Background New hospital staff represent a critical yet underexplored group in radiation safety research. Their initial perceptions and early experiences with safety systems are formative, shaping long-term professional behaviours and highlighting systemic gaps in onboarding and s...

Molecular detection and risk factors of carbapenemase -encoding gene among the Gram-negative uropathogens associated with catheter-associated urinary tract infection

Carbapenem-resistant Gram-negative bacteria frequently cause catheter-associated urinary tract infections (CA-UTIs). The objectives of this study included investigating prevalence, drug-resistance mechanisms, and risk factors associated with the infections caused by carbapenemase...

Impact of Smokeless Tobacco on Semen Quality: A Systematic Review and Meta‐Analysis

ABSTRACT Background Smokeless tobacco products are widely regarded as a safer alternative to smoking. However, a growing body of evidence points to harmful effects on male reproductive health. The aim of this systematic review and meta‐analysis was to assess the association betwe...

Cu-water Williamson nano-fluid in EMHD flow over an exponentially expanding sheet embedded in a Darcy–Forchheimer porous medium considering viscous dissipation

Abstract In this broadside, the unsteady magnetohydrodynamic (MHD) stream of a Williamson nano-fluid (WNF) established in a porous media has been considered, incorporating the belongings of heat generation/absorption, thermal radiation, and heat source. The commanding nonlinear p...

Improved photocatalytic water-splitting efficiency and superior optoelectronic aspects in a lead free CsRbGe(Cl,Br)6: Strain engineering

The realization of a sustainable fuel economy rests squarely on the development of earth-abundant, robust photocatalysts. Despite the remarkable optoelectronic performance of lead-halide perovskites, their commercial viability remains fundamentally obstructed by two persistent li...

β-carotene enhances drought tolerance in fenugreek by modulating antioxidant defense and redox homeostasis

Drought stress is one of the main abiotic factors that modulates the morphology and physiology of crops. This study investigated the effect of foliar application of β-carotene on the growth, physiological, and biochemical responses of fenugreek (Trigonella foenum-graecum L.) unde...

Comparative efficacy and safety of intra-articular versus intravenous tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis

Total knee arthroplasty (TKA) is frequently associated with considerable perioperative and postoperative blood loss, making tranexamic acid (TXA) a key component of modern blood-sparing protocols. Although both intravenous (IV) and intra-articular (IA) routes are widely used, the...

Association of organisational culture and internal participation with job satisfaction among physiotherapists: a cross-sectional study

Abstract This cross-sectional study aimed to examine the independent and combined relationships of organisational culture and internal participation with job satisfaction of physiotherapists. Data was collected through an online survey of licenced physiotherapists in Saudi Arabia...

Can small reductions in Rubisco content improve nitrogen use in wheat without negatively impacting biomass or grain yield?

In this study, the level of Rubisco protein was reduced in wheat using RNAi, to test the hypothesis that photosynthesis, growth, and grain yield could be maintained whilst improving nitrogen use efficiency. The RNAi Rubisco wheat plants, with a Rubisco activity of less than 70% o...

Development of efficient finite population mean estimators using transformed auxiliary variables and hierarchical clustering-based stratification

Abstract Efficient estimation of a finite population mean depends on both estimator formulation and the quality of the strata. This study develops three classes of mean estimators under stratified simple random sampling without replacement by integrating transformed auxiliary inf...

Sustainable use of phosphogypsum to enhance sandy soils fertility and wheat yield in arid environments

Abstract Purpose Sandy soils in arid regions have low fertility, poor structural stability, and limited water‐holding capacity. This study evaluated phosphogypsum (PG) as a soil amendment for improving sandy‐soil quality and wheat productivity under arid conditions. Methods A fie...

A Feature‐Enhanced Artificial Neural Network‐Assisted Adaptive Truncated EWMA Control Chart for Robust Monitoring of Contaminated Processes

ABSTRACT The use of conventional memory‐type control charts can be significantly hindered by the presence of outliers and contaminated observations, as these can lead to excessive false alarms and be difficult to detect true process shifts. To tackle the aforementioned problems,...

Medication reconciliation documentation and documented discrepancies in a tertiary Saudi hospital: a retrospective observational study

Abstract Introduction Medication reconciliation is a key patient-safety process during transitions of care, but its routine documentation and associated medication-list findings are not well described in Saudi tertiary hospital practice. This study aimed to characterize medicatio...