Taichung Hospital

Identification of holistic needs in people with chronic kidney disease

PURPOSE OF REVIEW: Chronic kidney disease (CKD) is a growing global health challenge with substantial physical, psychological, social, and practical consequences beyond impaired kidney function. This review examines the rationale for holistic needs assessment, summarizes availabl...

Progressive Conduction System Disease Preceding Hypertrophy in IVS4 + 919G > A Fabry Variant: a Population-based Electrocardiographic Study

BACKGROUND: The IVS4 + 919G > A variant is the most prevalent late-onset Fabry variant in East Asian populations, but its electrophysiological trajectory remains incompletely defined. METHODS: From a regional genetic screening program, 905 IVS4 + 919G > A carriers were identified...

Sex differences in the associations of body composition and PPARGC1A genetic variants with elevated pulse pressure

Pulse pressure (PP) is a hemodynamic marker for vascular aging. We investigated the sex-specific associations of bioelectrical impedance analysis (BIA)-derived body composition indices and PPARGC1A/VDR variants with elevated PP risk. This community-based study analyzed 5,829 adul...