Sysmex (Japan)

Rapid screening of urinary tract infections: quantitative flow cytometry versus dipstick testing in a hospital cohort

PURPOSE: We compared urine dipstick testing (DS) with quantitative flow cytometry (FC) and evaluated a diagnostic algorithm to optimise urinary tract infection (UTI) screening. METHODS: In this single-centre study, 5,124 consecutive urine samples were analysed in parallel using D...

Machine learning enables clinically feasible implementation of clot waveform analysis for differentiating causes of prolonged activated partial thromboplastin time

Abstract Activated partial thromboplastin time (APTT) is widely used as a coagulation screening test; nonetheless, its prolongation can result from diverse causes, complicating the diagnosis. Clot waveform analysis (CWA) has been proposed as a complementary method, although the c...

Exploring vertical genomic heterogeneity and chemotherapy response using targeted genomic sequencing in muscle-invasive bladder cancer

We performed a targeted genomic sequence of muscle-invasive bladder cancer (MIBC) tissues to investigate vertical intratumoral heterogeneity, invasion processes, and potential biomarkers of platinum-based neoadjuvant chemotherapy (NAC) efficacy in MIBC. Mutations in key genes tho...