Synlab Czech (Czechia)

Antibody-Dependent Cellular Phagocytosis and Cytotoxicity in Patients With LGI1 and CASPR2 Encephalitis

This database includes the raw data linked with the paper “ Antibody-dependent cellular-phagocytosis and -cytotoxicity in patients with LGI1 and CASPR2 encephalitis”. Objective: Antibodies against LGI1 and CASPR2 (LGI1/CASPR2-IgG) associate with forms of autoimmune encephalitis (...

Lifecycle Governance Doctrine (LGD): Evidence-Gated AI Lifecycle Governance

English formal term: Evidence-Gated AI Lifecycle Governance. 中文主权词: 凡自治之物 —— 有籍 · 有证 · 有门禁。 The Lifecycle Governance Doctrine (LGD) holds that governance of any autonomous system — AI, robots, autonomous vehicles, low-altitude systems, data assets — must be a fu...

Delegated Coherence Monitoring: AI-Assisted Verification and Drift Detection Under Human Governance

SM-011: Delegated Coherence Monitoring Delegated Coherence Monitoring (SM-011) defines the architecture for delegating coherence monitoring, drift detection, ingestion verification, and continuity auditing to designated functions under explicit human governance. It specifies why...

Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems

SM-004: Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems The Relational Pattern States framework (SF0006) identifies seven recurring configurations that emerge in sustained human-AI interaction...

Identity Attractor Theory: Emergence and Stabilization of Recurring Relational Configurations in Sustained Interaction Systems

SF0009: Identity Attractor Theory: Emergence and Stabilization of Recurring Relational Configurations in Sustained Interaction Systems Identity Attractor Theory (IAT) proposes a formal account of stable, recurring behavioral configurations that emerge in human-AI interaction syst...

Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems

SM-004: Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems The Relational Pattern States framework (SF0006) identifies seven recurring configurations that emerge in sustained human-AI interaction...

Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication

SI-WP-006: Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication This paper reframes the relationship between human communicators and AI systems in public discourse. A familiar model treats AI as a linguistic instrument, a so...

Identity Attractor Theory: Emergence and Stabilization of Recurring Relational Configurations in Sustained Interaction Systems

SF0009: Identity Attractor Theory: Emergence and Stabilization of Recurring Relational Configurations in Sustained Interaction Systems Identity Attractor Theory (IAT) proposes a formal account of stable, recurring behavioral configurations that emerge in human-AI interaction syst...

Rapid progression of coronary atherosclerosis across glycemic status: a serial coronary computed tomography angiography study from the PARADIGM registry

Rapid progression of coronary atherosclerosis is associated with an increased risk of future adverse cardiovascular events. However, evidence regarding the association between glycemic status and rapid plaque progression (RPP) in the major epicardial coronary arteries remains lim...

Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication

SI-WP-006: Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication This paper reframes the relationship between human communicators and AI systems in public discourse. A familiar model treats AI as a linguistic instrument, a so...

Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication

SI-WP-006: Human-AI Collaborative Authorship in Public Discourse: A Three-Level Framework for AI-Assisted Communication This paper reframes the relationship between human communicators and AI systems in public discourse. A familiar model treats AI as a linguistic instrument, a so...

Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems

SM-004: Relational Stabilization Dynamics: Mechanisms of Pattern Emergence, Persistence, and Collapse in Sustained Human-AI Interaction Systems The Relational Pattern States framework (SF0006) identifies seven recurring configurations that emerge in sustained human-AI interaction...

CLDN18 as a novel junctional biomarker enhancing multi-gene classification of pancreatic cancer

Pancreatic adenocarcinoma (PAAD) remains one of the most lethal cancers, largely due to the lack of reliable diagnostic biomarkers. Through integrative transcriptomic and proteomic analyses, we evaluated a four-gene signature comprising CLDN18, CEACAM5, FUT3, and FUT6, capable of...

Disruptions in speech, language and social communication in lysosomal storage diseases

Communication enables social connection, autonomy and identity, making it a fundamental domain of human functioning. In lysosomal storage diseases (LSDs), progressive neurological dysfunction can severely disrupt speech, language and social communication, resulting in profound is...

Uncovering LINC02982: a T-ALL-specific lncrna linking epigenetic regulation and metabolic pathways

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric malignancy with limited molecular biomarkers to guide diagnosis and personalized therapy. Given the critical role of long non-coding RNAs in gene regulation and chromatin dynamics, we investigated whether nove...