Swansea University

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS....

Refining the use of seed balls to support seagrass restoration

Abstract Seagrass ecosystems are experiencing rapid global decline, and current seed-based restoration efforts are frequently hindered by severe early-life bottlenecks such as decapod predation and bioturbation. To bypass these ecological feedbacks, encasing Zostera marina seeds...

Acoustic Controlof Spin States in Diamond Nitrogen-VacancyCentres

Abstract We report acoustic control of spin resonance in nitrogen-vacancy (NV–) centers in diamond using low-frequency free-space sound waves. Acoustic excitation redistributes spin populations between the |+1⟩ and |−1⟩ states, producing an asymmetric, tunable double-dip ODMR spe...

Does the AMPD1 C34T Polymorphism Influence Physical Performance in Elite Athletes?

Background/Objectives: Adenosine monophosphate deaminase deficiency has been implicated in impaired exercise capacity. We examined whether the AMPD1 C34T (rs17602729) genotype was associated with athlete status and performance in distance runners (DR) and rugby union (RU) athlete...

Managing sports with artificial intelligence: resistance and acceptance

Purpose This study aims to explore the determinants that shape the intentions of sports business managers to accept or object to the use of artificial intelligence (AI) within their organizations. This research addresses the gap in the management field regarding AI adoption in th...

From Public Good to Private Provision: The Role of Hospitality Workers in Gatekeeping Toilet Access

Public toilet closures in the UK, driven by austerity, have led to increasing reliance upon private or commercial facilities, such as toilets in bars and cafes. The extra labour required to maintain and monitor these toilets became especially visible under COVID-19 restrictions....

Bulldozing an immersed granular material in a confined channel

The motion of an immersed granular material in a channel is characterised by complex interactions among the grains, between the grains and the permeating liquid, and between the grains and the channel walls. Here, we develop a reduced-order continuum model for the bulldozing of a...

Understanding funding-related bias in gambling research: insights from unhealthy commodities industries and medical/pharmaceutical research – a scoping review

Despite the risk of funding-related bias (RoFRB) introduced by industry funding in gambling research, empirical investigations remain limited. To inform understanding of RoFRB in gambling research, this scoping review synthesized 52 peer-reviewed studies (2019–2024) spanning gamb...

Acoustic Emission Informed Assessment of Damage In Sicf/Sic CMC Via In Situ X-Ray Computed Tomography Under Monotonic And Cyclic Loading Conditions

Abstract The adoption of ceramic matrix composites (CMCs) in high performance engineering applications requires a comprehensive understanding of damage initiation and progression. Matrix crack onset and saturation are key damage states associated with continuous fibre-reinforced...

Meta-analysis and network meta-analysis of time-to-event outcomes with non-proportional hazards: a Bayesian time-varying hazard ratio approach

Abstract Background Meta-analyses of time-to-event (TTE) outcomes, particularly in Health Technology Assessment (HTA), commonly use a hazard ratio (HR) scale. However, non-proportional hazards in included trials create difficulties. Existing methods are either too complex or not...

Implementation of minimum unit pricing for alcohol in Scotland and subsequent rates of hospital-admitted self-harm: controlled interrupted time series analysis

BACKGROUND: Harmful alcohol use is a major modifiable risk factor for self-harm. We aimed to examine associations between minimum unit pricing for alcohol, introduced in Scotland in 2018, and rates of hospital-admitted self-harm. METHODS: Data were obtained from Public Health Sco...

Professional Segmentation as a Barrier to Reform in Turkish Nursing

This paper argues that segmentation within Turkish nursing is a major factor holding back the modernisation of nurse management. Since the millennium Türkiye's healthcare system has been transformed by NPM-style reforms that changed financing mechanisms and strengthened aspects o...