Swansea Bay University Health Board

Sushrutha’s Reflex: A Novel Clinical Sign for Detecting Focal Macular Surface Elevation

Purpose: To describe a novel clinical sign, eponymously named Sushrutha’s reflex, and to evaluate its diagnostic effectiveness for identifying focal retinal surface elevations, such as those found in central serous chorioretinopathy (CSCR) and pigment epithelial detachments in ey...

Human biomonitoring of occupational benzene exposure among petroleum-exposed workers in nigeria and its implications for public health surveillance

Benzene is an established human carcinogen and an important occupational hazard in petroleum-related work. Human biomonitoring can complement environmental monitoring by characterising internal exposure, yet biomonitoring evidence remains limited in many Sub-Saharan African occup...

Lymphocytosis as a biomarker for natalizumab treatment response in multiple sclerosis: The link with anti-drug antibodies

Background: Natalizumab is a high-efficacy therapy drug for multiple sclerosis that inhibits lymphocyte migration into the central nervous system, increasing lymphocyte counts in the peripheral blood. Anti-drug antibody responses may limit drug efficacy, but current guidance reco...

Evaluating the Impact of Entrustable Professional Activity Based Medical Student Teaching and Logbook Usage on Competence and Confidence in Peripheral Intravenous Cannulation

Introduction Entrustable Professional Activities (EPAs) are specific and measurable units of clinical practice used in competency-based training. Learners demonstrate skills to assessors who assign supervision levels for future practice. This study evaluated the impact of EPA-bas...

Clot microstructure in infective and non-infective exacerbation of COPD, are they different?

Objective Patients with Chronic Obstructive Pulmonary Disease (COPD) often develop exacerbations that could be infective or non-infective and are prone to develop thrombosis. To assess thrombogenicity in this group, a functional biomarker of clot microstructure namely fractal dim...

20 Updates on Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA: A cross-sectional study (The MIMOSA Study)

Abstract The MIMOSA (Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA) study is recruiting patients with a presumed diagnosis of glioblastoma (GBM) pre-operatively to receive advanced diffusion-weighted magnetic-resonance-imaging (DW-MRI) using the C...