Suzhou Guangji Hospital

Resting‐State and Task‐State Dual‐Paradigm fNIRS Study Reveals Dynamic Alterations in Brain Network Activity in Alzheimer's Disease With Behavioural and Psychological Symptoms

ABSTRACT Background Alzheimer's disease (AD) frequently presents with behavioural and psychological symptoms of dementia (BPSD), severely impacting prognosis. The dynamic brain network mechanisms remain unclear, and traditional neuroimaging faces limitations. Functional near‐infr...

Prediction of Claudin18.2 expression in gastric adenocarcinoma by habitat radiomics based on spectral CT

To explore the predictive value of habitat radiomics derived from Dual-layer spectral detector CT (DLSCT) for the preoperative evaluation of Claudin18.2 (CLDN18.2) expression in gastric adenocarcinoma. A retrospective cohort of 111 eligible patients with gastric adenocarcinoma wh...

Elevated Plasma DISC1 Levels Are Associated With Motivational Deficits in Medication‐Free Patients With Major Depressive Disorder: An Exploratory Study

ABSTRACT Disrupted‐in‐Schizophrenia 1 ( DISC1 ) has been implicated in major psychiatric disorders, but the relationship between circulating DISC1 protein and dimensional motivation and pleasure‐related features in major depressive disorder (MDD) is unknown. This exploratory cros...

Differential nodal topology in resting-state networks as a potential imaging marker for adolescent bipolar and depressive disorders

Overlapping clinical features and the absence of objective diagnostic markers frequently lead to the misdiagnosis of adolescent bipolar disorder (BD) as major depressive disorder (MDD). However, direct comparisons of functional brain network topology between adolescents with MDD...