Surrey and Borders Partnership NHS Foundation Trust

Applying a systemic approach that extends beyond the brain to Alzheimer’s disease pathogenesis

Traditional dementia research often isolates single aspects, biomarkers or symptoms, overlooking complex interactions shaping disease risk and progression. Lysosomal and mitochondrial dysfunction, reflecting systemic processes, may explain links between Alzheimer’s and metabolic,...

Food Allergies and Eating Disorders: An Exploration of Screening Prevalence and Associated Factors Among Adults

Background/Objectives: Food allergy (FA) affects up to 10% of adults and requires ongoing dietary vigilance that may increase vulnerability to eating disorders (EDs), yet evidence in adults remains limited. This study compared ED screening and history between adults with and with...

Are different consumer sleep technologies measuring the same essential aspects of sleep?

Abstract Study objectives Consumer sleep technologies (CSTs) enable low-burden longitudinal sleep monitoring, and their output measures are often interpreted as equivalent to polysomnography (PSG) measures. We applied a measurement reliability-aware approach to determine whether...

Exploring Fitness to Participate in Court Proceedings Among Defendants with Fetal Alcohol Spectrum Disorder: A Systematic Scoping Review

<title>Abstract</title> Fetal Alcohol Spectrum Disorder (FASD) is a lifelong neurodevelopmental condition resulting from prenatal alcohol exposure, affecting both cognitive and behavioural functioning. Within the legal system, determining whether an individual can effectively par...