Subang Jaya Medical Centre

Exploring the functions of NKG7 in CD4+ and CD8+ T cells during malaria

Malaria, caused by Plasmodium parasites, is a significant global health issue. CD4 + and CD8 + T cells are important for immunity against Plasmodium infections, but the specific roles of many immune-related effector molecules in T cells remain poorly defined. Here, we investigate...

Unveiling differential gene expression and pathways in clear cell renal cell carcinoma with sarcomatoid transformation

Background Sarcomatoid transformation in clear cell renal cell carcinoma (ccRCC) is associated with highly aggressive clinical behaviour and poor prognosis. The molecular basis underlying this transformation remains poorly defined. Methods Formalin-fixed paraffin-embedded tumour...