Structural Genomics Consortium

A validated antibody toolbox for ALS research

A substantial fraction of amyotrophic lateral sclerosis (ALS)-associated proteins remains poorly characterized, in part because of the limited availability of validated research antibodies. We established knockout (KO)-based antibody characterization workflows and demonstrated th...

Enabling Computational Exploration of an Expanding Academic Chemistry Space

Abstract Ultralarge virtual libraries have become a cornerstone of modern early stage drug discovery, enabling the rapid exploration of billions of compounds. The chemical space accessible to most screening campaigns, however, remains constrained not by the availability of buildi...