Stoke Mandeville Hospital

Primary diffuse leptomeningeal melanomatosis presenting as chronic meningitis and dense spinal plaques

Primary diffuse leptomeningeal melanomatosis (PDLM) is an exceptionally rare and aggressive central nervous system melanocytic tumour, often masquerading as inflammatory or infective leptomeningeal disease. A woman in her early 60s presented with hydrocephalus and diffuse leptome...