Stem Cell Institute

Machine learning–driven decoding of maternal immune signatures in repeated pregnancy loss

Repeated pregnancy loss (RPL) is a multifactorial condition in which the underlying immunological mechanisms, particularly the disruption of maternal-fetal tolerance, remain incompletely understood. Although immune tolerance is critical for pregnancy success, the specific immune...

Growth factor-based manufacturing of human pluripotent stem cell-derived cardiomyocytes using the vertical wheel bioreactor system

Abstract Background Multiple protocols have been reported for the large-scale generation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in bioreactors using small molecules; however, no comparable bioreactor-based methods have been established using growth facto...