State Key Laboratory of Animal Nutrition

Pediococcus acidilactici Long21 Alleviates Intestinal Sensitivity and Improves Gut Health in German Shepherd Dogs by Regulating Intestinal Metabolic Profiles

Background: Canine intestinal sensitivity is a multifactorial functional gastrointestinal disorder characterized by recurrent soft feces, impaired nutrient utilization, and low-grade intestinal inflammation, and it acts as a major trigger for chronic gastrointestinal discomfort i...

Multi-omics elucidate octapeptin mechanisms in alleviating intestinal injury in mice challenged with ETEC K88 via modulated microbial and host pathways

K88 (ETEC K88) in mice. Octapeptin ameliorated intestinal injury by modulating gut microbiome-host interactions. When compared with ETEC K88 mice, octapeptin significantly attenuated growth retardation, systemic oxidative stress, pro-inflammatory cytokine elevation, and ileal mor...