Institution
St Vincent's Hospital Melbourne
Recent research
- Health & Medicine
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over the last two decades, but it is unclear whether this reflects fewer complications, improved s...
- BiologyOpen access
Infradian rhythms of human heart rate reveal distinct multiday cycle periods in healthy adults
BACKGROUND: Chronobiology research has historically focused on circadian rhythms; however, longer infradian rhythms are prevalent in human physiology and may have important implications for health and wellbeing. Previous studies have identified widespread infradian rhythms across...
- Health & Medicine
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over time, and this is likely to be multifactorial. In addition to better oncologic treatments, sa...
- Health & MedicineOpen access
Abstract Topic Benign Disease: Gastro-Esophageal Reflux and Hiatal Hernia Background Hiatus hernias are relatively common and can be associated with adverse symptoms and serious complications. Operative repair is indicated in this patient group for symptom management and the prev...
- Society & Economics
= 125) completed a word list and motor sequence task in counterbalanced order with either a shared or distinct sequence structure. In contrast to Mosha and Robertson (2016), we found that a shared ordinal structure between the declarative and motor sequence tasks did not facilita...
- Health & MedicineOpen access
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
OBJECTIVE: Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual-related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about-monthly cy...
- Health & MedicineOpen access
A multi-centre study of belatacept and sirolimus for islet transplantation
Abstract Aims/hypothesis Islet transplantation is an appropriate treatment for selected individuals with type 1 diabetes mellitus and hypoglycaemia unawareness. The gold standard of maintenance immunosuppression to prevent allograft rejection is calcineurin inhibitor-based therap...
- Health & MedicineOpen access
Impact of socioeconomic status on treatment and survival in multiple myeloma in Australia
<title>Abstract</title> Outcomes in multiple myeloma (MM) have improved significantly but remain heterogeneous. We assessed the impact of non-biological social determinants of health on treatment and survival outcomes in Australia using data from the Australian and New Zealand My...
- Health & Medicine
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive...
- Health & MedicineOpen access
BACKGROUND: South Asian women, like many other culturally and linguistically diverse populations in Australia, remain under-represented in breast cancer screening, perpetuating inequities in early detection and treatment. To explore perspectives of South Asian women and general p...
- Society & EconomicsOpen access
Lemborexant Versus Sedative-Hypnotics in the Treatment of Insomnia: A Systematic Narrative Review
Abstract Purpose Sedative-hypnotics for insomnia carry risks of adverse effects and dependence. We reviewed how lemborexant, a dual orexin receptor antagonist (DORA), compares with sedative-hypnotics (benzodiazepines and z-drugs) in adults with insomnia across sleep, adverse even...
- Health & MedicineOpen access
Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy
Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...
- Health & MedicineOpen access
Abstract Background and Objectives Patients with systemic lupus erythematosus (SLE) are at increased risk of osteoporosis due to chronic inflammation, prolonged glucocorticoid (GC) exposure, and treatment-related factors. Hydroxychloroquine (HCQ), a cornerstone of SLE therapy, ha...