St Thomas' Hospital

Recurrent PDGFRB-Mutations in the Epithelioid Variant of Fibrous Papules

Fibrous papule (FP) is a common benign dermal mesenchymal lesion presenting as a solitary, dome-shaped papule mostly located on the nose. The morphologic spectrum is broad, and a number of variants have been described, including hypercellular, clear cell, pigmented, pleomorphic,...

A multimodal manual therapy, exercise, and psychological intervention for painful diabetic neuropathy: the NeuOst feasibility randomised controlled trial.

Introduction: People with painful diabetic neuropathy lack effective and tolerable treatments. Physical and psychological interventions may help but require further study and combination to maximise effects. Objectives: This single-site, 3-arm, parallel, randomised feasibility tr...

Comparing the utility of FDG PET-CT and contrast-enhanced CT in patients with oesophagogastric adenocarcinoma treated with neoadjuvant chemotherapy

Abstract Background 2-deoxy-2[ 18 F]fluoro-D-glucose positron emission tomography-CT (FDG PET-CT) is established in staging oesophagogastric adenocarcinoma. It has an emerging role in assessing response to neoadjuvant chemotherapy (NACT) but its benefits over contrast-enhanced CT...

Visual impairment certifications in England over 16 years: annual numbers attributable to age-related macular degeneration, glaucoma, diabetes and hereditary eye disease

Individuals meeting certain criteria of sight impairment or severe sight impairment are eligible for a Certificate of Vision Impairment (CVI), which can facilitate access to support [ 1 , 2 ]. When the certificate is issued, the main cause of vision impairment is recorded. Here,...

Improving diabetes management in older adults with cancer: a quality improvement project to enhance monitoring during steroid-based systemic anti-cancer therapy

PURPOSE: Older adults undergoing systemic anti-cancer therapy (SACT) with steroids are at high risk of developing steroid-induced hyperglycaemia (SIH). However, monitoring and management remain inconsistent. This quality improvement project (QIP) involved developing and evaluatin...

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activatio...

P1.244. Robotic-Assisted Versus Conventional Minimally Invasive Oesophagectomy for Oesophageal Cancer: A Comparative Meta-Analysis of Perioperative and Oncological Outcomes

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – technique Background Robotic-assisted minimally invasive oesophagectomy (RAMIE) is increasingly adopted to improve surgical precision, mediastinal dissection, and surgeon ergonomics. However, its clinical...

Quality‐of‐life and late effects after transabdominal cerclage: A nationwide matched cohort study

INTRODUCTION: A transabdominal cerclage is inserted to prevent recurrent midtrimester loss and spontaneous preterm birth. The transabdominal cerclage often remains as a permanent foreign body for years. Synthetic materials within the abdomen, cesarean birth, and prior adverse pre...