St Mark's Hospital

Fecal microbiota transplant in the treatment of inflammatory bowel diseases: new perspectives on delivery, mechanism, and clinical positioning

Abstract The gut microbiota, a complex and dynamic community of microorganisms, has emerged as a crucial determinant of human health and well-being in recent years. This microbial ecosystem plays a pivotal role in various physiological processes, including nutrient metabolism, im...

UK consensus recommendations for onward testing for Lynch syndrome in patients with deficient mismatch repair (dMMR) non-colorectal/non-endometrial cancers

Accepted: 2026) UK consensus recommendations for onward testing for Lynch Syndrome in patients

A qualitative exploration of information access and provision for cancer survivors experiencing chronic bowel symptoms after pelvic radiotherapy: informing a framework to guide improvements to information provision

Abstract Purpose For people living with and beyond cancer, access to clear, accurate, relevant information is crucial for meaningful participation in shared decision-making and is associated with better quality-of-life. Many cancer patients who undergo pelvic radiation experience...

Capturing quality of life in pouch anal and vaginal fistula: development of PAVF-QoL-14, a patient-reported outcome measure

Abstract Introduction Perianal pouch fistula can significantly affect quality of life, yet no disease-specific patient reported outcome measure (PROM) exists. We have developed and validated a 14-item PROM—the Pouch Anal and Vaginal Fistula Quality of Life scale (PAVF-QoL-14). Me...

Benchmarking UK Lynch syndrome colonoscopy surveillance: quality metrics and diagnostic yield from the National Endoscopy Database

Abstract Colonoscopy quality and diagnostic outcomes in Lynch syndrome have historically been heterogeneous. Following the introduction of the Lynch syndrome Bowel Cancer Screening Programme (BCSP), we assessed colonoscopy quality and diagnostic yield in Lynch syndrome using the...

National multi-specialty robotic surgery training curriculum and implementation for UK surgical residents: a delphi consensus

Abstract Robotic-assisted surgery is now established across multiple surgical specialties in the United Kingdom, yet training for surgical residents remains variable, resource-dependent, and insufficiently standardised at national level. This study sought multispecialty expert co...