St. John's College

Decoupling Ecological and Pathogenic Roles: Helicobacter pylori as a Gastric Hegemon Maintaining Order or Amplifying Dysbiotic Chaos

Abstract Gastric dysbiosis refers to disease-associated alterations in microbial composition and between-individual variability. We postulate that Helicobacter pylori (H. pylori or Hp) exerts a context-dependent ecological effect across the Correa cascade—the histopathological pr...

Implementing prospective probabilistic scheduling of surgical cases to yield more predictable utilisations

We studied the impact of a prospective, probabilistic scheduling method to replace surgeon-led booking, balancing contradictory goals of maximizing theatre utilised time while minimizing risk of over-utilised time. Implemented in an NHS Scotland hospital, the study analyzed 2420...

Characterisation of liver disease using quantitative MRI: report of the imaging arm of the ELEGANCE study

Evolving disease aetiology and rising prevalence of chronic liver disease are driving an increase in hepatocellular carcinoma (HCC). Non-contrast quantitative MRI (qMRI) has shown promising capability for characterising liver health and risk of liver related outcomes, but has not...