St James's University Hospital

How to manage: acute-on-chronic liver failure

Acute on chronic liver failure has emerged as a distinct clinical entity over the past few decades. While mortality remains highest for patients who develop liver and multiple non-liver organ failures, earlier recognition of the syndrome, including identification and management o...

44 UK radiotherapy practice in volume delineation–data from the APPROACH trial (ISRCTN:1339049) radiotherapy quality assurance (RTQA) programme benchmark outlining case

Abstract Introduction Interobserver variation in radiotherapy contouring can affect protocol compliance and the robustness of clinical trial outcomes. The APPROACH (Analysis of Proton vs Photon Radiotherapy in Oligodendroglioma and Assessments of Cognitive Health) trial protocol...