St. Charles Hospital

Cascade Remodeling through Late-Stage Electrophilic Fluorination in a Bis-Spiroketal Framework

Abstract Cascade reactions efficiently generate molecular complexity but are often incompatible with the late-stage diversification of highly functionalized natural products due to competing degradation pathways. Herein, we demonstrate that electrophilic fluorination can serve as...

Alpha-Gal Syndrome Is More than Meats the IgE: A Patient Survey of Symptoms, Diagnosis, and Burdens

Background/Objectives: Alpha-gal syndrome (AGS) is an allergic condition that results in delayed symptoms in response to exposure to mammalian products. There is limited research on which healthcare professionals (HCPs) are diagnosing AGS, types of symptoms, time to reactions, an...