St. Boniface Hospital

Food-Derived l -tryptophan and α-Casein (90–95) Differentially Potentiate Porcine Calcium-Sensing Receptor Signaling and Improve Enteroendocrine–Epithelial Responses Under Peptidoglycan Challenge

Abstract The calcium-sensing receptor (CaSR) is a nutrient-sensing class C G protein-coupled receptor implicated in intestinal hormone release, yet the signaling pharmacology of the porcine receptor and its relevance to epithelial homeostasis remain poorly defined. Here, a stable...