Srinakharinwirot University

Development of loop-mediated isothermal amplification (LAMP) combined with a lateral flow dipstick DNA biosensor for detection of α thalassemia 1 [Southeast Asia (SEA), --SEA deletion]

This study aimed to develop a one-step loop-mediated isothermal amplification combined with a lateral flow dipstick (LAMP-LFD) DNA biosensor for the detection of α 0 -thalassemia (SEA deletion). Genomic DNA was obtained from 48 α 0 -thalassemia (SEA deletion)-positive and 48 (SEA...

Strengthening of Recycled Aggregate Concrete with Novel Natural Banana Fiber Rope Confinement

This study investigates the effectiveness of banana rope confinement, a biodegradable and low-cost natural fiber technique, in enhancing the compressive behavior and seismic performance of concrete incorporating recycled materials. An experimental program was conducted on cylindr...

Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay

ABSTRACT The global spread of multidrug-resistant tuberculosis (MDR-TB) remains a major challenge to tuberculosis control programs, particularly in resource-limited settings where access to rapid molecular drug-susceptibility testing is limited. Resistance to isoniazid and rifamp...

A Smartphone-Based Silver Nanoparticle Assay for Detecting Enhanced Gamma-Aminobutyric Acid Content in Germinated Rice via Metabolic Modulation

Abstract This study aimed to increase the γ-aminobutyric acid (GABA) content in rice grains and develop surface-modified silver nanoparticles (AgNPs) as a simple colorimetric chemosensor for its detection. To stimulate GABA production, rice grains from the Kor Kho 6 (RD6) and Kha...

Mangrove canopy-height estimation using LiDAR and multispectral remote sensing: linking spatiotemporal species composition to restoration baselines

Canopy height is an important indicator of mangrove forest structure, ecological functioning, and restoration development; however, field measurements are spatially limited by cost, accessibility, and survey effort. This study mapped mangrove canopy height in Trat Province, Thail...

Anti-proliferative and anti-inflammatory potential of 2-chloro-3-((4-hydroxyphenyl)amino)naphthalene-1,4-dione through targeting TNF-α/IL-8 and NF-κB signaling in HCT116 cancer cells: a comprehensive in silico docking and in vitro study

Colorectal cancer (CRC) is closely associated with chronic inflammation, and the NF-κB pathway acts as a central regulator of the inflammatory response that promotes tumor progression. In this study, we examined the anticancer and anti-inflammatory potential of anilino-1,4-naphth...

Development of Aqueous Two-Phase System for Eco-Friendly and Decolorized Triterpenoids Extraction of Centella asiatica Optimized by Response Surface Methodology

Centella asiatica (L.) Urban extracts are widely used in food, cosmetic, and pharmaceutical products. Conventional solvent extraction requires organic solvents and often produces dark green extracts due to chlorophyll co-extraction, limiting their industrial applications. This st...

Effect of used cooking oil sludge loading on diesel-range fraction yield and fuel properties from ternary waste pyrolysis oil: Toward practical blendstock assessment

Tri-pyrolysis oil (TPO) produced from oil palm fresh fruit bunches (PFFB), medical waste polypropylene bottles (MWPB), and used cooking oil sludge (UCOS) was separated by atmospheric fractional distillation into pyro-gasoline (PG), pyro-diesel (PD), and heavy fractions at UCOS lo...

Split Nitrogen Application Improves Yield and Partial Factor Productivity of Nitrogen in Rice (cv. RD49) Under Low-Fertility Sandy Loam Soil

Nitrogen (N) management is critical for improving rice productivity, but increasing N inputs may reduce N-use productivity when grain production does not increase proportionally. This study evaluated the effects of urea rate and application method on grain weight and partial fact...

A qualitative study of sustainability oriented financial decision making and gender equity among working-age women in Thailand

Thai working-age women possess deep, culturally embedded sustainability values derived from Buddhist philosophical traditions and the Sufficiency Economy Philosophy, yet face systematic structural exclusion from sustainable investment markets. This qualitative study recruited 35...

Academic burnout among female adolescents: A resource-based model of social support, perfectionism, and academic self-efficacy

Academic burnout is an increasingly recognized psychosocial challenge among adolescents exposed to sustained academic demands. Guided by Conservation of Resources theory, this study develops and tests a resource-based model examining how social support and perfectionism are assoc...

Beyond Attractions: Understanding Tourist Satisfaction in Sustainable Creative Tourism

ABSTRACT Understanding tourists' evaluations of creative tourism destinations remains important for sustainable destination development. This study examined tourists' expectations and satisfaction regarding sustainable creative tourism products in Sathing Phra District, Songkhla...

Hot-gas pyrolysis of fresh palm fruit using a cross-draft biomass gasifier–burner: Product recovery, fuel properties, energy performance, and emissions

Conventional biomass pyrolysis commonly relies on electric furnaces or liquefied petroleum gas (LPG) burners as external heat sources, which limits its practicality for decentralized applications in biomass-rich areas. To reduce dependence on these external commercial energy sour...

Association between short-form video media use and inattentive, hyperactive-impulsive, and oppositional defiant symptoms in Thai preschool children

Media use has previously been bidirectionally associated with attentional problems in children. Evidence regarding short-form video, a relatively new type of media accessible through personal devices such as smartphones and tablets, remains limited, particularly in preschool popu...

Percutaneous transvenous mitral commissurotomy during pregnancy: a contemporary Southeast Asian experience

Abstract Background Severe rheumatic mitral stenosis during pregnancy is associated with substantial maternal and fetal morbidity because physiological hemodynamic changes may precipitate heart failure and pulmonary hypertension. Percutaneous transvenous mitral commissurotomy (PT...

Discovery of Bis-ThioureaDerivatives as Human DNATopoisomerase IIα Inhibitors with Potent Anticancer Effects

Abstract DNA topoisomerase IIα (Topo IIα) is essential for maintaining genomic stability during DNA replication and mitosis and is highly expressed in cancer cells, making it a promising target for anticancer therapy. In this study, bis-thiourea derivatives were investigated for...

Serum decoy receptor 3 (DcR3) concentrations and associations with clinical parameters in Plasmodium vivax and Plasmodium falciparum malaria

Decoy receptor (DcR3) is a soluble member of the tumor necrosis factor receptor superfamily with immunomodulatory properties that is elevated in several inflammatory and infectious diseases. However, its role in malaria remains poorly understood. This study investigated serum DcR...

Landscape of industry-sponsored oncology trials across the Thai Society of Clinical Oncology (TSCO): a 12-year multicenter analysis

Cancer remains a major global health challenge and is a leading cause of morbidity and mortality in Thailand. Industry-sponsored oncology trials (ISOTs) provide critical access to innovative therapies, including targeted agents, immunotherapies (IO), and antibody–drug conjugates...