Spitalul Clinic Județean de Urgență Cluj-Napoca

Limited Gut Microbiome Differences Between Relapsing–Remitting and Secondary Progressive Multiple Sclerosis: A Shotgun Metagenomic Study

The gut microbiome may contribute to multiple sclerosis (MS) pathophysiology, but its relationship with disease phenotype and progression remains unclear. To characterize taxonomic and functional gut microbiome differences between relapsing–remitting MS (RRMS) and secondary progr...

Real-World Clinical Management of Keratoconus in Europe and the Middle East: A Multicountry Survey on Diagnostic and Surgical Practices (Keratoconus in Mind - KIM Project)

Purpose: This study aimed to describe the current management of patients with keratoconus in European and Middle Eastern countries through the collection of real-world data from clinicians actively managing keratoconus. Methods: Computer-assisted web interviewing survey targeting...

Longitudinal Stability of the Gut Microbiota in Relapsing–Remitting Multiple Sclerosis: A Prospective Observational Study

The gut microbiota plays a key role in immune regulation in multiple sclerosis (MS), yet longitudinal data on microbiome dynamics and their relationships with disability and biomarkers remain limited. This study aimed to identify longitudinal gut microbiome changes in patients wi...

Minimalist Footwear and Knee Joint Loading During Walking in Healthy Adults: A Systematic Review of Evidence for Osteoarthritis Prevention

Background/Objectives: Minimalist footwear has been proposed as a passive means of reducing knee loading, but its effects during walking in healthy adults, the population relevant to primary prevention of knee osteoarthritis (KOA), have not previously been synthesized. Methods: F...

Discontinuous Peripheral Punctate Echogenic Foci in Thyroid Nodules: A New Sonographic Pattern Suggestive of Papillary Carcinoma

Background: Ultrasound risk stratification systems for thyroid nodules worldwide describe different types of echogenic foci, including punctate echogenic foci (microcalcifications), coarse internal calcifications, and peripheral (rim) calcifications (complete or incomplete), with...

Perceived Stress and Domain-Specific Physical Activity in Relation to Anxiety and Somatic Symptom Burden Among Romanian Adults: A Cross-Sectional Online Survey

Background and Objectives: Physical activity may relate to mental health differently depending on whether it is performed at work, for transport, or during leisure. Evidence regarding this distinction in Romanian community samples remains limited, and it is unclear whether these...