Institution
Sparrow Health System
UShealthcare
Recent research
- Health & MedicineOpen access
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
BACKGROUND: Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin-6 (IL-6) inhibitor, is the only FDA-approved treatment for adult patients with iMCD. Limited...