Southern California Eye Institute

Optic Disc and Retinal Strain Due to Vertical Duction

Purpose: To compare two-dimensional optic disc and retinal vessel strains due to vertical versus horizontal eye rotations in younger and older subjects using confocal scanning laser ophthalmoscopy (cSLO). Methods: In a younger subject group (n = 10; range, 18-39 years; mean age ±...

Wnt Pathway Agonism as a Therapeutic Strategy for Retinal Vascular Diseases: A Narrative Review of Evidence to Date

Breakdown of the blood–retinal barrier (BRB) is implicated in many blinding retinal diseases, including diabetic macular edema, neovascular age-related macular degeneration, and retinal vein occlusion. Anti-vascular endothelial growth factor (anti-VEGF) therapies or laser photoco...