Soroka Medical Center

The burden of blast injuries on a level i trauma center: a comparative analysis of blast versus blunt trauma

PURPOSE: We hypothesized that blast trauma results in a greater institutional resource burden than blunt trauma. METHODS: This retrospective study compared blast trauma patients (N = 321) to blunt trauma patients (N = 9,172). A Propensity Score Matching (PSM) on Age, Sex and Inju...

Metabolic changes following relief of upper airway obstruction promote rebound weight gain in mice

The mechanisms driving weight gain after removal of upper airway obstruction and restoration of normal respiration remain unclear. We examined how increased respiratory loading alters energy balance, body weight, and metabolism in mice during and after airway obstruction (AO). In...

From Rapid Progression to Long-Lasting Complete Response: A Wide Range of Ripretinib Activity for Metastatic GIST—A Real-World Cohort

Background: Ripretinib, a switch-control kinase inhibitor approved for advanced gastrointestinal stromal tumor (GIST), inhibits primary and secondary KIT and PDGFRA mutations. Real-world data from Western and Middle Eastern populations remain limited. We report outcomes from a mo...

Pulmonary exacerbations in primary ciliary dyskinesia

Abstract Primary ciliary dyskinesia (PCD) is a rare inherited disorder of motile ciliary dysfunction characterized by impaired mucociliary clearance, chronic sino-pulmonary disease, and progressive bronchiectasis. Pulmonary exacerbations (PEx) are a major contributor to morbidity...

Pregnancy after Hemithyroidectomy: Increased Risk of Gestational Overt Hypothyroidism Despite Favorable Obstetric Outcomes: A Nationwide Study

Background: To assess the association between preconception hemithyroidectomy and the risk of gestational hypothyroidism and obstetric outcomes. Methods: This nationwide population-based retrospective cohort study compared euthyroid pregnant women with a history of hemithyroidect...

Corpus callosum fractional anisotropy from routine diffusion tensor imaging predicts dementia in older adults beyond clinical risk factors

Dementia arises from multifactorial neurodegenerative processes, with growing evidence implicating blood-brain barrier dysfunction, neuroinflammation, and vascular injury as contributors to progressive brain tissue damage. Because decline in white matter microstructural integrity...